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US 2022/0017487 A1Published application
Deuterated compounds and uses thereof
AssigneeX4 Pharmaceuticals, Inc.
InventorsElyse Marie Josee Bourque, Renato Skerlj
Life of this patent
Estimating the term…
Abstract
The present invention provides deuterium-enriched CXCR4 inhibitors, pharmaceutical compositions, and methods of using such deuterium-enriched CXCR4 inhibitors and pharmaceutical compositions to treat, prevent, or ameliorate a disease, disorder, or condition such as cancer or WHIM syndrome.
Claims20
A compound of formula I:
- or a pharmaceutically acceptable salt thereof, wherein:
- each of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, and R27 is independently H or D;
- provided that at least one of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, and R27 is D.
Dependencies are inferred from the claim text.