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US 2022/0017475 A1Published application
Polymorphic compounds and uses thereof
AssigneeAldeyra Therapeutics, Inc.
InventorsStephen Gitu MACHATHA, Jonathan J. LOUGHREY, Hannah Ruth MCLACHLAN, Gregor SNEDDON
Life of this patent
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Abstract
The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions in which aldehyde toxicity is implicated in the pathogenesis by the administration of small molecule therapeutics acting as a scavenger for toxic aldehydes.
Claims22
1-25. (canceled)
Compound A:
- wherein the compound is crystalline.
A compound selected from one of the following:
- compound 2:
- of Forms A, B or C;
- compound 3:
- of Forms A, B or C;
- compound 4:
- compound 5:
- of Forms A, B or C;
- compound 6:
- compound 7:
- of Forms A, B or C;
- compound 8:
- of Forms A or B;
- compound 9:
- compound 10:
- compound 11:
- and
- compound 12:
14 more elements
Dependencies are inferred from the claim text.