Tube-containing medical devices with bioactive luminal wire

A tube-containing medical device kit, comprising:

• a tube-containing medical device including an access opening positionable exterior with respect to a subject, a fluid communication opening positionable within the subject to fluidically communicate with a body fluid of the subject, and an elongated lumen therebetween;
• and
• a luminal wire insertable within the elongated lumen, wherein the luminal wire has a length that is within 5% to 100% of the elongated lumen, and has an x-y cross-sectional diameter sufficiently smaller than an x-y cross-sectional diameter of the elongated lumen to allow fluid flow therebetween, wherein the luminal wire is bioactive.

A method of protecting the lumen of a tube-containing medical device, comprising:

• inserting a fluid communication opening of a tube-containing medical device within a body of a subject, the tube-containing medical device further comprising an access opening exterior to the body to access an elongated lumen of the tube-containing medical device in fluid communication with the fluid communication opening;
• and
• sliding a luminal wire within the elongated lumen, wherein the luminal wire has a length that is within 5% to 100% of the elongated lumen, and has an x-y cross-sectional diameter sufficiently smaller than an x-y cross-sectional diameter of the elongated lumen to allow fluid flow therebetween, wherein the luminal wire is bioactive.