Hypertonic antimicrobial therapeutic compositions
AssigneeAim Targeted Therapies, Inc.
InventorGlenn ABRAHMSOHN
Life of this patent
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Abstract
Therapeutic compositions, primarily for topical application, and methods of making and using the composition. Pharmaceutical compositions formulated for specific forms of administration are also provided.
Claims22
-12. (canceled)
A method for treating a condition comprising administering or applying to a patient a composition comprising:
- a) a chloride salt;
- b) a source of bicarbonate;
- c) a source of hypochlorite;
- and
- d) an antimicrobial agent selected from the group consisting of biguanides, bisbiguanides, triguanides and analogs thereof;
- wherein the patient has a condition selected from the group consisting of a wound, a bacterial infection, a viral infection, a fungal infection, an inflammation, angiogenesis, and pain reduction.
The method of claim 1, wherein the pH of the composition is in the range of about 7.2 to about 9.5.
A method for treating a condition, comprising administering to a patient in need thereof a therapeutic composition comprising:
- a) a chloride salt;
- b) a source of bicarbonate;
- c) a source of hypochlorite;
- and,
- d) an antimicrobial agent selected from the group consisting of biguanides, bisbiguanides, triguanides and analogs thereof;
- wherein the amount of the chloride salt in the composition is sufficient to render the composition hypertonic;
- and, wherein the composition is alkaline.
A method for treating a condition, comprising administering to a patient in need thereof a therapeutic composition comprising:
- a) a salt selected from sodium chloride and potassium chloride;
- b) a source of carbonate selected from the group consisting of sodium bicarbonate, potassium bicarbonate, calcium bicarbonate and ammonium bicarbonate;
- c) N-chloro tosylamide;
- d) chlorhexidine;
- e) a source of peroxide selected from hydrogen peroxide, carbamide peroxide and sodium percarbonate;
- f) poloxamer 237;
- g) lauramine oxide;
- and,
- h) gluconolactone.
A method for treating a condition, comprising administering to a patient in need thereof a therapeutic composition comprising:
- a) a chloride salt;
- b) a source of bicarbonate;
- c) an oxygen producing compound;
- d) an antimicrobial agent;
- and,
- e) a surfactant;
- wherein the concentration of the chloride salt in the composition is in the range of at least 0.3M to about 8M;
- wherein the concentration of the source of bicarbonate is at least 8M;
- and,
- wherein the composition is alkaline.
Dependencies are inferred from the claim text.