Compositions that enhance iron absorption and methods of use thereof

A pharmaceutical formulation for use in treating a disease or disorder associated with iron deficiency,

• wherein the pharmaceutical formulation comprises:
• a) pharmaceutically active ingredients comprising, consisting essentially of, or consisting of a therapeutically effective amount of each of at least two free amino acids selected from a first group of amino acids consisting essentially of aspartic acid, glutamic acid, glutamine, and glycine,
• wherein the therapeutically effective amount of each of the at least two free amino acids is sufficient to treat the disease or disorder associated with iron deficiency in the subject;
• b) at least one a pharmaceutically inactive ingredient;
• and
• c) optionally further comprising pharmaceutically active ingredients comprising, consisting essentially of, or consisting of a therapeutically effective amount of each of at least one free amino acid selected from a second group of amino acids consisting essentially of cysteine, histidine, and isoleucine,
• sufficient to treat the disease or disorder associated with iron deficiency in the subject.

A method for treating a disease or disorder associated with iron deficiency in a subject in need thereof, the method comprising:

• administering a pharmaceutical composition to the subject in need thereof,
• wherein the pharmaceutical composition comprises:
• a) pharmaceutically active ingredients comprising, consisting essentially of, or consisting of a therapeutically effective amount of each of at least two free amino acids selected from a group of amino acids consisting essentially of aspartic acid, glutamic acid, glutamine, and glycine, wherein the therapeutically effective amount of each of the at least two free amino acids is sufficient to treat the disease or disorder associated with iron deficiency in the subject;
• and
• b) at least one a pharmaceutically inactive ingredient.

A method for treating a disease or disorder associated with iron deficiency in a subject in need thereof, the method comprising:

• administering a pharmaceutical composition to the subject in need thereof,
• wherein the pharmaceutical composition comprises:
• a) pharmaceutically active ingredients comprising, consisting essentially of, or consisting of a therapeutically effective amount of each of at least two free amino acids selected from a first group of amino acids consisting essentially of aspartic acid, glutamic acid, glutamine, and glycine,
• wherein the therapeutically effective amount of each of the at least two free amino acids is sufficient to treat the disease or disorder associated with iron deficiency in the subject;
• b) at least one a pharmaceutically inactive ingredient;
• and
• c) optionally further comprising pharmaceutically active ingredients comprising, consisting essentially of, or consisting of a therapeutically effective amount of each of at least one free amino acid selected from a second group of amino acids consisting essentially of cysteine, histidine, and isoleucine,
• wherein the therapeutically effective amount of each of the at least one free amino acids is sufficient to treat the disease or disorder associated with iron deficiency in the subject.