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US 2022/0010258 A1Published application
Device that can serve as a hemato-encephalitic barrier model
AssigneesUniversite De Poitiers, Centre Hospitalier Universitaire De Poitiers
InventorsGUYLÈNE PAGE, Hanitriniaina RABEONY, Damien CHASSAING, Emilie DUGAST, Thierry JANET
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Abstract
The present invention relates to a device which can serve as a model of a hemato-encephalic barrier (HEB) comprising two compartments in which certain cell types are arranged. The invention also relates to the method for preparing said device and the use thereof as a model of the HEB.
Claims14
A device comprising two compartments that are separated by a porous synthetic membrane, a luminal compartment comprising endothelial cells and pericytes, and an abluminal compartment comprising astrocytes.
Dependencies are inferred from the claim text.