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US 2022/0010033 A1Published application
Carboxymethyl Cellulose and Method of Preparation
AssigneeCore Scientific Creations Ltd.
InventorsShani ELIYAHU-GROSS, Yuval YASKIL
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AssigneeCore Scientific Creations Ltd.
InventorsShani ELIYAHU-GROSS, Yuval YASKIL
Estimating the term…
Provided is a method for producing a cellulose derivative. The method includes forming a first reaction product by reacting non-oxidized cellulose with at least one first alkalization agent in the presence of at least one suitable solvent, wherein the first reaction product includes a non-oxidized alkali-cellulose. The method further includes forming a second reaction product by reacting a monohalo-organic compound with a second alkalization agent in a solution, wherein the second reaction product includes a saturated solution and a sediment. The method further includes increasing a temperature of the saturated solution and dissolving at least a portion of the sediment, and reacting the non-oxidized alkali-cellulose with the second reaction product to form an improved carboxymethyl cellulose.
1-36.
A hemostatic device comprising a plurality of repeating units of non-oxidized cellulose, wherein the plurality of repeating units of the non-oxidized cellulose comprise a plurality of side chains of CH2COONa bound to one of three hydroxyl groups of each repeating unit, and wherein the plurality of side chains comprise an ionic end group of a carboxyl group (COO—) with a Na+ counter ion.
A method of stopping or reducing bleeding from a wound, comprising applying a hemostatic device comprising a plurality of repeating units of non-oxidized cellulose to a bleeding wound without a need of application of external pressure to the hemostatic device, wherein the plurality of repeating units of the non-oxidized cellulose comprise a plurality of side chains of CH2COONa bound to one of three hydroxyl groups of each repeating unit, and wherein the plurality of side chains comprise an ionic end group of a carboxyl group (COO—) with a Na+ counter ion.
Dependencies are inferred from the claim text.