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US 2022/0008697 A1Published application
Balloon inflation composition and system for in vivo location confirmation
AssigneeChonnam National University Hospital
InventorsJa Hae KIM, Yun Chul PARK
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Abstract
A method for in vivo location determination of a balloon catheter according to an embodiment of the present disclosure includes inserting into a body of a subject a balloon catheter including a balloon inflated by a balloon inflation composition including a radioactive isotope as an active ingredient; and detecting the in vivo location of the radioactive isotope. The balloon inflation composition for in vivo location determination of a balloon catheter allows accurate and safe determination of the location of the balloon catheter inserted into the body from outside the body.
Claims20
1:
- A method for in vivo location determination of a balloon catheter, the method comprising:
- inserting into a body of a subject a balloon catheter including a balloon inflated by a balloon inflation composition comprising a radioactive isotope as an active ingredient;
- and
- detecting the in vivo location of the radioactive isotope.
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2:
- The method of claim 1, wherein the radioactive isotope is included in an amount in which radiation is emitted at an intensity of 0.001 cps to 99,999 cps.
3:
- The method of claim 1, wherein the radioactive isotope emits beta particles or gamma particles.
4:
- The method of claim 1, wherein the balloon inflation composition is formed in any one of liquid, gaseous, gel, and solid phases.
5:
- A system for in vivo location determination of a balloon catheter comprising:
- a balloon inflation composition for in vivo location determination of a balloon catheter comprising a radioactive isotope;
- a balloon catheter including a balloon which is inflated by the balloon inflation composition while being inserted into the body;
- and
- a radioisotope detector configured to detect radiation radiated from the radioactive isotope from outside the body.
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6:
- The system of claim 5, wherein the balloon inflation composition includes the radioactive isotope in an amount in which radiation is emitted at an intensity of 0.001 cps to 99,999 cps.
7:
- The system of claim 5, wherein the balloon inflation composition is formed in any one of liquid, gaseous, gel, and solid phases.
8:
- The system of claim 5, wherein the radioisotope detector is a gamma particle detector.
9:
- The system of claim 5, wherein the location of the balloon of the balloon catheter inserted into the body is determined in real time.
10:
- The system of claim 9, wherein when the balloon inflation composition is inserted into the balloon of the balloon catheter, the in vivo location of the balloon is determined within 5 seconds.
11:
- A system for in vivo location determination comprising:
- a catheter device which has a radioactive material and is provided to be inserted into a body;
- and
- a detector configured to detect radiation radiated from the radioactive material approaching a target site by movement of the catheter device.
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12:
- The system of claim 11, wherein the catheter device comprises:
- a guide wire provided to be inserted into the body;
- and
- a balloon catheter provided to be movable along the guide wire.
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13:
- The system of claim 11, wherein the radioactive material is fixedly located at at least one of the guide wire and the balloon catheter.
14:
- The system of claim 11, wherein the balloon catheter comprises:
- a tube having a hollow portion through which the guide wire passes;
- and
- a balloon member provided to be inflatable on the tube.
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15:
- The system of claim 14, wherein the radioactive material is disposed adjacent to the balloon member.
16:
- The system of claim 14, wherein the radioactive material is located inside the balloon member.
17:
- The system of claim 16, wherein the radioactive material is fixedly disposed on one of an inner wall of the balloon member and the tube.
18:
- The system of claim 14, wherein the balloon member is operated in a deflated state and an inflated state in which an outer surface thereof is inflated from the deflated state to press an inner wall of a blood vessel with an outer surface thereof, and
- the radioactive material is provided to maintain the same position inside the balloon member, when the balloon member is in the deflated state and the inflated state.
19:
- The system of claim 11, wherein the radioactive material is formed in a solid phase.
20:
- The system of claim 11, wherein the detector comprises:
- a probe located at a target site outside the body to detect radiation radiated from the radioactive material;
- and
- a console unit configured to receive a signal detected by the probe and display measurement results.
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