US 2022/0008633 A1 · PARABIOTIC DIALYSIS SYSTEMS AND TECHNIQUES

Abstract

The present teachings generally include parabiotic dialysis systems and techniques. For example, the present disclosure includes parabiotic liver dialysis, e.g., for use in settings with limited resources. To this end, a parabiotic liver dialysis system may include a device having a semipermeable membrane with an average pore size that allows for the passage of albumin therethrough. In such a system, a first extracorporeal circuit may connect the device to the vascular system of a first animal (e.g., a liver patient), and a second extracorporeal circuit may connect the device to the vascular system of a second animal (e.g., a human with normal liver function), where the exchange of albumin therebetween is facilitated through the device. The present disclosure also includes various safety measures for parabiotic dialysis systems and techniques, such as biometric verification systems and techniques.

Claims20

Dependent claims

A parabiotic liver dialysis system, the system comprising:

a device having a first side and a second side, the device including a semipermeable membrane between the first side and the second side, the semipermeable membrane having an average pore size allowing for passage of molecules having a molecular weight of between about 70 kilodaltons (kDa) and 140 kDa;
a first extracorporeal circuit including one or more first fluid connectors for connecting the first side of the device to the vascular system of a first animal;
a second extracorporeal circuit including one or more second fluid connectors for connecting the second side of the device to the vascular system of a second animal;
a first pump in fluid communication with at least one of the first and second extracorporeal circuits;
and
a driver mechanically coupled to the first pump, the driver configured to drive the first pump using energy from an energy source.

3 more elements

Dependencies are inferred from the claim text.

Parabiotic dialysis systems and techniques

Life of this patent

Parabiotic dialysis systems and techniques

Life of this patent

Abstract

Claims20