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US 2022/0008567 A1Published application
Liquidly injectable, self-stabilizing biopolymers for the delivery of radionuclide
AssigneeDuke University
InventorsAshutosh Chilkoti, Jeffrey L. Schaal, Wenge Liu
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Abstract
Described herein are compositions for liquidly injectable, self-stabilizing biopolymers for the delivery of radionuclide brachytherapy. Also described herein are methods of using the compositions.
Claims44
A composition comprising:
- a first collection of self-assembling conjugates comprising at least one radionuclide coupled to a first elastin-like polypeptide;
- and
- a chemotherapeutic.
A method of treating cancer in a subject in need thereof, the method comprising co-administration of:
- a therapeutically effective amount of a composition comprising a first collection of self-assembling conjugates comprising at least one radionuclide coupled to a first elastin-like polypeptide;
- and
- a therapeutically effective amount of chemotherapeutic.
Dependencies are inferred from the claim text.