Novel nanoparticles of antiretroviral drugs, their preparation and their use for the treatment of viral infections
AssigneesCentre National De La Recherche Scientifique, Institut Pasteur, Universite Paris-Saclay
InventorsHervé HILLAIREAU, Elias FATTAL, Giovanna GIACALONE, Héla SAIDI, Marie-Lise GOUGEON, Marion QUAILLET, Sarah PALLARA
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Abstract
The present application relates to nanoparticles including an antiretroviral drug and chitosan and optionally one or more metal cation, their use for treating viral infections, their process of preparation and the pharmaceutical compositions including the same.
Claims20
A method for treating and/or preventing HIV and/or the symptoms thereof comprising administering by the sub-cutaneous or intramuscular route a nanoparticle comprising an antiretroviral drug encapsulated by an encapsulation complex, said complex comprising chitosan.
A nanoparticle comprising an antiretroviral drug encapsulated by an encapsulation complex, said complex comprising chitosan and Fe3+.
A nanoparticle comprising enfuvirtide encapsulated by an encapsulation complex comprising chitosan.
Dependencies are inferred from the claim text.