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US 2022/0008535 A1Published application
Methods and compositions for the treatment and/or prevention of type 1 diabetes
AssigneeThe Curators of the University of Missouri
InventorHabib Zaghouani
Life of this patent
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Abstract
The disclosure relates generally to methods and compositions of treating or preventing diabetes mellitus by administering to a subject a composition comprising an amount of stem and/or progenitor cells and at least one antigen-specific therapy.
Claims13
A composition comprising an amount of purified allogenic endothelial progenitor cells and an amount of at least one immunoglobulin-polypeptide chimera, wherein the immunoglobulin-peptide chimera expresses a disease-specific T- or B-cell epitope.
A composition comprising:
- an amount of cells, wherein the cells consist essentially of purified allogenic endothelial progenitor cells;
- and
- an amount of at least one immunoglobulin-polypeptide chimera, wherein the immunoglobulin-peptide chimera expresses a disease-specific T- or B-cell epitope.
Dependencies are inferred from the claim text.