Multivalent feline vaccine
AssigneeIntervet Inc.
InventorsZhichang Xu, Rhonda LaFleur, Ian Tarpey
Life of this patent
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Abstract
The present invention provides new multivalent vaccines for felines. The present invention also provides methods of making and using the multivalent vaccines alone or in combinations with other protective agents.
Claims21
1-23. (canceled)
A vaccine to aid in the prevention of disease due to feline calicivirus (FCV) comprising an alphavirus RNA replicon particle that encodes one or more FCV capsid proteins and a modified live feline pathogen selected from the group consisting of a modified live feline viral rhinotracheitis virus (FVR), a modified live feline panleukopenia virus (FPLV), a modified live Chlamydophila felis, and any combination thereof, and a pharmaceutically acceptable carrier.
A vaccine to aid in the prevention of disease due to FCV comprising a Venezuelan Equine Encephalitis (VEE) alphavirus RNA replicon particle that encodes a virulent systemic feline calicivirus (VS-FCV) capsid protein, a modified live feline viral rhinotracheitis virus (FVR), a modified live feline panleukopenia virus (FPLV), a modified live Chlamydophila felis and a pharmaceutically acceptable carrier;
- wherein the VS-FCV capsid protein comprises an amino acid sequence comprising at least 95% identity with the amino acid sequence of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.