Methods, compositions, and kits for treating ocular diseases
OwnerJohn VAN DUZER, Greg WILLIAMSinventors
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Abstract
Provided herein are methods of treating an ocular disease associated with one or more nonsense mutation in a subject using one or more amino-glycosides and/or derivatives thereof. The pharmaceutical compositions and kits containing one or more aminoglycosides and/or derivatives thereof for treating the ocular disease are disclosed.
Claims19
(canceled)
A method of treating an ocular disease associated with one or more nonsense mutations in a subject, comprising intravitreally administering to said subject a therapeutically effective amount of one or more aminoglycosides selected from the group consisting of NB118, NB122, NB124, NB124-MeS, NB127, NB128, and NB157.
(canceled)
11-13. (canceled)
A formulation for use in treating an ocular disease associated with one or more nonsense mutations in a subject, comprising one or more aminoglycosides selected from the group consisting of NB118, NB122, NB124, NB124-MeS, NB127, NB128, and NB157, wherein the formulation is for intravitreal administration.
(canceled)
(canceled)
A kit for use in treating an ocular disease associated with one or more nonsense mutations in a subject, comprising one or more aminoglycos ides selected from the group consisting of NB118, NB122, NB124, NB124-MeS, NB127, NB128, and NB157.
20-22. (canceled)
Dependencies are inferred from the claim text.