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US 2022/0008352 A1Published application
Composition for the Transdermal Delivery of Fentanyl
AssigneeKindeva Drug Delivery L.P.
InventorsAdam S. Cantor, Terrance W. Ocheltree, Cynthia A. Robles
Life of this patent
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Abstract
A transdermal drug delivery composition comprises an acrylate copolymer and from about 8% to about 30% by weight fentanyl. A transdermal fentanyl delivery composition comprising methyl laurate or tetraglycol as a permeation enhancer is also provided. The transdermal drug delivery compositions can be used to make a transdermal drug delivery device for the delivery of fentanyl.
Claims12
A transdermal patch for administering fentanyl through the skin comprising:
- (a) a backing layer;
- and
- (b) a polyacrylate adhesive reservoir disposed on the backing layer, at least the skin contacting surface of said reservoir being adhesive;
- comprising a single phase polymeric composition free of undissolved fentanyl and containing an amount of fentanyl sufficient to induce and maintain analgesia in a human for at least three days.
1 more element
A monolithic transdermal patch for administering fentanyl through the skin comprising:
- a. a backing layer;
- and
- b. a polyacrylate adhesive reservoir disposed on the backing layer, at least the skin contacting surface of said reservoir being adhesive, comprising a single phase polymeric composition to be free of undissolved components and containing an amount of fentanyl sufficient to induce and maintain analgesia in a human for at least three days.
Dependencies are inferred from the claim text.