Compositions and methods for treating viral infections
AssigneesThe University of Sydney, Westmead Institute For Medical Research, Western Sydney Local Health District
InventorsMark William Douglas, Mohammed Eslam, George Jacob, Anis Khan
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Abstract
The present disclosure relates to compositions and methods for treating viral infections and in particular for treating hepatitis B and hepatitis D viral infections. A method of treating a hepatitis B virus infection in a subject the method comprising administering to the subject an inhibitor wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism in the subject.
Claims96
A method of treating a hepatitis B virus infection in a subject the method comprising administering to the subject an inhibitor wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism in the subject.
A method of reducing the concentration of hepatitis B surface antigen in serum of a subject the method comprising administering to the subject an inhibitor wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism in the subject.
A method of treating a hepatitis D virus infection in a subject the method comprising administering to the subject an inhibitor wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism in the subject.
A composition comprising an inhibitor and a pharmaceutically acceptable carrier wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism.
A method of diagnosing susceptibility to hepatitis B virus infection in a subject the method comprising detecting the presence of a TM6SF2 polymorphism in a nucleic acid sample obtained from the subject.
Dependencies are inferred from the claim text.