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US 2021/0388037 A1Published application
Leader sequence for yeast
AssigneeBASF SE
InventorsJingping Zhong, Xuqiu Tan, Melissa Ann Scranton
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Abstract
The present invention relates to a leader peptide which promotes the secretion of recombinant proteins and a nucleic acid sequence encoding the leader peptide as well as expression cassettes, vectors and host cells comprising this leader sequence. Also disclosed is a method for producing a protein using this leader peptide.
Claims27
An isolated leader peptide selected from the group consisting of:
- (a) a peptide comprising the amino acid sequence according to SEQ ID No. 1 or a functional variant thereof;
- (b) a peptide comprising an amino acid sequence selected from the group of SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4 and SEQ ID No. 5, or a functional variant thereof;
- and
- (c) a peptide comprising an amino acid sequence which is at least 80% identical to the amino acid sequence according to any one of SEQ ID Nos. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4 and SEQ ID No. 5.
1 more element
Dependencies are inferred from the claim text.