Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia

A drug delivery contact lens, comprising:

• a) a contact lens comprising a first surface and a second surface;
• and
• b) said contact lens further comprising at least one coating provided on at least a portion of said first surface, said second surface, or a combination thereof as opposed to within said contact lens;
• 1) said coating comprising at least one three dimensional structure;
• and
• 2) said three dimensional structure comprising:
• a. one or more drug reservoir layers;
• wherein said one or more drug reservoir layers comprise one or more drugs;
• and
• b. one or more barrier layers;
• wherein said one or more barrier layers modulate the release of said one or more drugs from said drug delivery contact lens;
• wherein said one or more drug reservoir layers, said one or more barrier layers, or a combination thereof, are oriented vertically, horizontally, or a combination thereof, relative to each other;
• and
• further wherein said one or more drugs can treat, prevent, control, reduce the severity, or reduce the progression of eye infections, eye inflammations, or combinations thereof, in a subject;
• further wherein said one or more drugs are released from said drug delivery contact lens in a pharmaceutically effective amount to treat, prevent, control, reduce the severity, or reduce the progression of eye infections, eye inflammations, or combinations thereof, in a subject when said drug delivery contact lens is operably engaged with the eye of said subject.