Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing
AssigneeAlbert Einstein College of Medicine
InventorsDavid SHARP, Brian O'ROURKE
Life of this patent
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Abstract
Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kif19 and Cep192. Methods and compositions are provided for enhancing wound healing, treating fibrosis, reducing scarring and treating nerve pain.
Claims22
A method of treating metastasis or inhibiting metastasis in a subject having a cancer comprising administering to the subject an amount of an inhibitor of KIF19 or of an inhibitor of Kif19 gene product, or an inhibitor of CEP192 or of an inhibitor of Cep192 gene product, effective to treat metastasis or inhibit metastasis.
(canceled)
A method of treating fibrosis or scarring, or of inhibiting fibrosis or scarring, in a subject comprising administering to the subject an amount of an inhibitor of KIF19 or of an inhibitor of Kif19 gene product, or an inhibitor of CEP192 or of an inhibitor of Cep192 gene product, effective to treat fibrosis or scarring, or inhibit fibrosis or scarring.
(canceled)
A method of treating pain associated with wound healing in a subject having a wound comprising administering to the subject an amount of an inhibitor of CEP192 or of an inhibitor of Cep192 gene product effective to treat pain associated with wound healing.
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Dependencies are inferred from the claim text.