Back to results
US 2021/0333282 A9Published application
Articles and methods directed to personalized therapy of cancer
AssigneesHesperix SA, The Scripps Research Institute
InventorsAlexey Vyacheslavovich Stepanov, Dmitry Dmitrievich Genkin, Richard A. Lerner, Alexey Anatolievich Belogurov, Alexander Gabibovich Gabibov, Jia Xie
Life of this patent
Estimating the term…
Abstract
Described are methods for providing personalized medicine for the treatment of B cell malignancies including lymphoma. The methods make use of Chimeric Antigen Receptor (CAR) technology.
Claims25
A method of treating cancer in a subject comprising concomitantly administering:
- CAR-expressing T-cells, wherein the CAR comprises an antigen binding domain that specifically binds a cancer-specific antigen in a cancer-specific manner;
- and
- a vaccine comprising a polypeptide or a nucleic acid expressing the cancer-specific antigen, or a cancer-specific fragment thereof.
Dependencies are inferred from the claim text.