# US 2021/0330902 A1 · System for gravity inclusion of powder into a medical delivery flow stream > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0330902 A1 - Document ID: US20210330902A1 - Status: Published application - Kind: A1 - Application number: 17/241,616 - Filed: 2021-04-27 - Published: 2021-10-28 - Earliest claimed: 2020-04-23 - Inventors: John H. Burban; John W. Shanahan; Michael R. Spearman; Craig J. Cuta; Keith A. Roberts - Web page: https://patentgrep.com/patent/US20210330902A1 ## CPC - A61M 13/00: Insufflators for therapeutic or disinfectant purposes {, i.e. devices for blowing a gas, powder or vapour into the body (hand-held units in which gas flow is produced by muscular energy at the moment of use B05B11/062)} - A61B 17/00491: {Surgical glue applicators} - A61B 2017/00522: {Sprayers} - A61M 15/0066: {with means for varying the dose size} - A61M 39/229: {Single-way cut-off valves} - A61M 2202/064: Powder - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A method and apparatus deliver dry, flowable hemostatic powder into a gas flow stream by gravity delivery within a body of the apparatus. The hemostatic powder is then carried with the gas out of the apparatus into an elongated delivery tube inserted into a patient. Delivery of the powder into the gas flow stream creates a bolus of powder and air which becomes more uniformly distributed as it passes through the elongated delivery tube. ## Claims ### Claim 1 A method of delivering dry hemostatic powder to an internal operation site or wound site of mammals, comprising the steps of: (a) extending a distal end of an elongated tubular delivery channel to a position that an emitting opening of said delivery channel is adjacent to said internal operation site or wound site; (b) providing a hand-held application device comprising a handle end and a forward end connected to a proximal end of the elongated tubular delivery channel, generating a conveying gas flow containing pressurized gas to mix with dry powder, a receptor for a neutral pressure particulate dry hemostatic powder gravity feeding cartridge, and an internal gas flow path from the handle end to the proximal end and passing under the receptor; (c) engaging the neutral pressure particulate dry hemostatic powder gravity feeding cartridge onto the receptor; (d) providing a gas conveying tube connected to the flow path at the handle end of the hand-held application device; (e) providing gas under pressure to the gas conveying tube to increase gas pressure and cause gas flow through the internal gas flow path and under the receptor; (f) gravity dropping the dry hemostatic powder from a bottom of the cartridge into the internal gas flow path through the receptor; (g) carrying the dropped dry hemostatic powder in the internal gas flow into the proximal end of the elongated tubular delivery channel; and (h) delivering the dropped dry hemostatic powder carried in the internal gas flow path to the internal operation site or wound site to assist clotting of blood at the operation site or wound site through the elongated tubular delivery channel. ### Claim 2 (depends on 1) The method of claim 1 wherein the dropped dry hemostatic powder is dropped into the internal gas flow while gas pressure above the dry hemostatic powder in the cartridge is lower than gas pressure within the internal gas flow path. ### Claim 3 (depends on 2) The method of claim 2 wherein the gas pressure in the cartridge is reduced by delivering the dropped dry hemostatic powder into the internal gas flow path creating an increased pressure differential between the gas pressure above the dry hemostatic powder in the cartridge and the gas pressure within the internal gas flow path, and intermittently gas in the internal gas flow path with form a bolus of gas and flow up through the dry hemostatic powder in a bottom section of the cartridge to reduce the pressure differential between the gas pressure above the dry hemostatic powder in the cartridge and the gas pressure within the internal gas flow path, without creating a new gas pressure differential between the gas pressure above the dry hemostatic powder in the cartridge and the gas pressure within the internal gas flow path where the gas pressure in the cartridge never exceeds the gas pressure in the internal gas flow path. ### Claim 4 (depends on 1) The method of claim 1 wherein dropped dry hemostatic powder is initially carried in the internal gas flow path at a point below the connector as a first bolus of dry hemostatic powder in air separated by volumes of air with a lower concentration of dry hemostatic powder than is present in the first bolus of dry hemostatic powder in air. ### Claim 5 (depends on 2) The method of claim 2 wherein dropped dry hemostatic powder is initially carried in the internal gas flow path at a point below the connector as a first bolus of dry hemostatic powder in air separated by volumes of air with a lower concentration of dry hemostatic powder than is present in the first bolus of dry hemostatic powder in air. ### Claim 6 (depends on 3) The method of claim 3 wherein dropped dry hemostatic powder is initially carried in the internal gas flow path at a point below the connector as a first bolus of dry hemostatic powder in air separated by volumes of air with a lower concentration of dry hemostatic powder than is present in the first bolus of dry hemostatic powder in air. ### Claim 7 (depends on 1) The method of claim 1 wherein providing gas under pressure to the gas conveying tube is initiated by a stopcock or valve on the hand-held application device that allows pressure to flow from a gas cylinder or gas pressure line into internal gas flow path in aa vector from the handle end to the elongated tubular delivery channel. ### Claim 8 (depends on 5) The method of claim 5 wherein providing gas under pressure to the gas conveying tube is initiated by a stopcock or valve on the hand-held application device that allows pressure to flow from a gas cylinder or gas pressure line into internal gas flow path in aa vector from the handle end to the elongated tubular delivery channel. ### Claim 9 (depends on 6) The method of claim 6 wherein providing gas under pressure to the gas conveying tube is initiated by a stopcock or valve on the hand-held application device that allows pressure to flow from a gas cylinder or gas pressure line into internal gas flow path in aa vector from the handle end to the elongated tubular delivery channel. ### Claim 10 (depends on 9) The method of claim 9 wherein the first bolus of dry hemostatic powder in air at least partially merges with the volumes of air with a lower concentration of dry hemostatic powder after entering the elongated tubular delivery channel. ### Claim 11 (depends on 1) The method of claim 1 wherein pressure is maintained at approximately equal or less than levels between the cartridge and the internal gas flow path by a gas conductive tube between the cartridge and the internal gas flow path. ### Claim 12 An apparatus for delivering dry hemostatic powder to an internal operation site or wound site of mammals comprising: a hand-holdable device having a handle end and a forward end; the handle end of the hand-holdable device having a coupling element configured to connect to a gas pressure source and a distal end of the hand-hold-able device having a delivery connector configured to connect to an elongated tubular delivery channel; an open passageway comprising an internal gas flow path between the coupling element and the distal end of the hand-holdable device; the internal gas flow path intersecting with and connecting to a receptor for a neutral pressure particulate dry hemostatic powder gravity feeding cartridge; and a trigger within the handle end of the hand-holdable device which opens and closes an opening for hemostatic gravity feed from the cartridge while there is gas flow from the handle end towards the coupling elements and the distal end of the hand-holdable device. ### Claim 13 (depends on 12) The apparatus of claim 12 wherein the neutral pressure particulate dry hemostatic powder gravity feeding cartridge is dry-flowable powder engaged with the receptor for the neutral pressure particulate dry hemostatic powder gravity feeding cartridge and the receptor is positioned at a relatively upper side of the hand-holdable device. ### Claim 14 (depends on 12) The apparatus of claim 12 wherein on a surface of the hand-holdable device opposite to the receptor for the neutral pressure particulate dry hemostatic powder gravity feeding cartridge is a movable stopper that when open allows gravity feeding of dry hemostatic powder from the neutral pressure particulate dry hemostatic powder gravity feeding cartridge into the internal gas flow path, and when the stopper is closed, prevents gravity feeding of dry hemostatic powder from the neutral pressure particulate dry hemostatic powder gravity feeding cartridge into the internal gas flow path. ### Claim 15 (depends on 13) The apparatus of claim 13 wherein on a surface of the hand-holdable device opposite to the receptor for the neutral pressure particulate dry hemostatic powder gravity feeding cartridge is a movable stopper that when open allows gravity feeding of dry hemostatic powder from the neutral pressure particulate dry hemostatic powder gravity feeding cartridge into the internal gas flow path, and when the stopper is closed, prevents gravity feeding of dry hemostatic powder from the neutral pressure particulate dry hemostatic powder gravity feeding cartridge into the internal gas flow path. ### Claim 16 (depends on 12) The apparatus of claim 12 wherein there is a gas conductive tube between the cartridge and the internal gas flow path so that pressure is maintained at approximately equal or less than levels between the cartridge and the internal gas flow path. ### Claim 17 (depends on 13) The apparatus of claim 13 wherein there is a gas conductive tube between the cartridge and the internal gas flow path so that pressure is maintained at approximately equal or less than levels between the cartridge and the internal gas flow path. ### Claim 18 A method of delivering dry hemostatic powder to an internal operation site or wound site of mammals, comprising the steps of: (a) extending a distal end of an elongated tubular delivery channel to a position that an emitting opening of said delivery channel is adjacent to said internal operation site or wound site; (b) providing a hand-held application device comprising a handle end and a forward end connected to a proximal end of the elongated tubular delivery channel, generating a conveying gas flow containing pressurized gas to mix with dry powder, a receptor for a neutral pressure particulate dry hemostatic powder gravity feeding cartridge, and an internal gas flow path from the handle end to the proximal end and passing under the receptor; (c) engaging the neutral pressure particulate dry hemostatic powder gravity feeding cartridge onto the receptor; (d) providing a gas conveying tube connected to the flow path at the handle end of the hand-held application device; (e) providing gas under pressure to the gas conveying tube to increase gas pressure and cause gas flow through the internal gas flow path and under the receptor; (f) gravity dropping the dry hemostatic powder from a bottom of the cartridge into the internal gas flow path through the receptor; (g) carrying the dropped dry hemostatic powder in the internal gas flow into the proximal end of the elongated tubular delivery channel; and (h) delivering the dropped dry hemostatic powder carried in the internal gas flow path to the internal operation site or wound site to assist clotting of blood at the operation site or wound site through the elongated tubular delivery channel, wherein the dropped dry hemostatic powder is dropped into the internal gas flow while gas pressure above the dry hemostatic powder in the cartridge is lower than gas pressure within the internal gas flow path, and wherein the gas pressure in the cartridge is reduced by delivering the dropped dry hemostatic powder into the internal gas flow path, the dropped dry hemostatic powder creating an increased pressure differential between gas pressure above the dry hemostatic powder in the cartridge and gas pressure within the internal gas flow path, and intermittently gas in the internal gas flow path with form a bolus of gas and flow up through the dry hemostatic powder in a bottom section of the cartridge to reduce the pressure differential between the gas pressure above the dry hemostatic powder in the cartridge and the gas pressure within the internal gas flow path, without creating a new gas pressure differential between the gas pressure above the dry hemostatic powder in the cartridge and the gas pressure within the internal gas flow path where the gas pressure in the cartridge never exceeds the gas pressure in the internal gas flow path. ### Claim 19 (depends on 18) The method of claim 18 wherein dropped dry hemostatic powder is initially carried in the internal gas flow path at a point below the connector as a first bolus of dry hemostatic powder in air separated by volumes of air between at least one subsequent additional bolus of dry hemostatic powder with a lower concentration of dry hemostatic powder than is present in the first bolus of dry hemostatic powder in air. ### Claim 20 (depends on 18) The method of claim 18 wherein dropped dry hemostatic powder is initially carried in the internal gas flow path at a point below the connector as a first bolus of dry hemostatic powder in air separated by volumes of air with a lower concentration of dry hemostatic powder than is present in the first bolus of dry hemostatic powder in air.