Antimicrobial adhesive copolymer compositions
AssigneeRhianna Pauline Stevens
InventorsRhianna Pauline Stevens, Emma Jenkins
Life of this patent
Estimating the term…
Abstract
Improved antimicrobial adhesive copolymer compositions for wound closure or surgical-site closure are provided. The antimicrobial adhesive copolymer compositions comprise cyanoacrylate-based tissue adhesive monomers and long-chain quaternary ammonium compounds (QUATs), or long-chain quaternary phosphonium compounds (QUPTs). The antimicrobial adhesive copolymer compositions offer advantages in wound closure or surgical-site closure with bactericidal and bacteriostatic effects on Gram-positive and Gram-negative organisms.
Claims16
An antimicrobial adhesive copolymer composition for wound closure, comprising:
- a cyanoacrylate component;
- and
- a charged quaternary ammonium component or a charged quaternary phosphonium component, wherein the charged quaternary ammonium component or the charged quaternary phosphonium component comprises at least one reactive alkene group.
An antimicrobial adhesive copolymer composition for wound closure, comprising:
- a chemical component resulting from a reaction between a formaldehyde component and a cyanoacetate component or a cyanoacetic acid component;
- and
- a charged quaternary ammonium component or a charged quaternary phosphonium component, wherein the charged quaternary ammonium component or the charged quaternary phosphonium component comprises at least one reactive alkene group.
A method for treatment or prevention of infection at a wound site or a surgical site, the method comprising adhering the wound site or the surgical site closed or partially closed with, or injecting or placing into the wound site or the surgical site, a chemical solution comprising i) a cyanoacrylate component, or a chemical component resulting from a reaction between a) a formaldehyde component and b) any cyanoacetate component or a cyanoacetic acid component;
- and ii) a charged quaternary ammonium component or a charged quaternary phosphonium component.
Dependencies are inferred from the claim text.