# US 2021/0330641 A1 · Pharmaceutical Preparations > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0330641 A1 - Document ID: US20210330641A1 - Status: Published application - Kind: A1 - Application number: 17/339,183 - Filed: 2021-06-04 - Published: 2021-10-28 - Earliest claimed: 2013-01-17 - Assignees: Symrise AG - Applicants: Symrise AG - Inventors: Elke Köck; Jakob Ley; Veronika Somoza; Kathrin Liszt; Sabine Widder - Web page: https://patentgrep.com/patent/US20210330641A1 ## CPC - A61K 31/365: Lactones - A23F 3/405: {Flavouring with flavours other than natural tea flavour or tea oil} - A23F 5/465: {Flavouring with flavours other than natural coffee flavour or coffee oil} - A23L 2/52: Adding ingredients (adding preservatives A23B70/10) - A23L 27/86: {Addition of bitterness inhibitors} - A23L 33/10: using additives (addition of substantially indigestible substances A23L33/21) - A61K 31/341: not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine - A61K 31/353: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin - A61K 47/22: Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones - G01N 33/5044: {involving specific cell types} - A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs - A61K 9/0056: {Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals} - A61K 9/0058: {Chewing gums (non-medicinal aspects, preparing chewing gum A23G4/00; chewing gum for care of the teeth or oral cavity, e.g. with breath freshener A61Q11/00)} - A61K 9/0095: {Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches (A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006)} - A61K 9/19: lyophilised {, i.e. freeze-dried, solutions or dispersions (lyophilised products with subsequent particle size reduction A61K9/14; granules or pellets made by lyphilisation A61K9/1682; solid oral dosage forms made by lyophilisation A61K9/2095; lyophilisation additives A61K47/00)} - A61K 9/4875: {Compounds of unknown constitution, e.g. material from plants or animals (oils, fats, waxes, shellac A61K9/4858)} - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23F: COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION ## Abstract Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents. ## Claims ### Claim at position 1 -15. (canceled) ### Claim 16 A method for reducing and/or inhibiting secretion of gastric acid induced by food constituents, comprising: administering a gastric acid-inhibiting substance selected from the group consisting of homoeriodictyol and/or eriodictyol to a human who has previously consumed a gastric acid-stimulating component selected from the group consisting of caffeine, theobromine and mixtures thereof and wherein the gastric acid-inhibiting substance is administered prior to gastric acid stimulation in the human by the gastric acid-stimulating component and which is in an amount which inhibits the gastric acid-stimulating effect of the gastric acid-stimulating component in the person. ### Claim 17 (depends on 16) The method of claim 16, wherein the gastric acid-inhibiting substance is administered in amounts of from 0.1 mg/kg to 1,000 mg/kg. ### Claim 18 (depends on 16) The method of claim 16, wherein the gastric acid-inhibiting substance is administered in amounts of from 0.1 mg/kg to 500 mg/kg. ### Claim 19 (depends on 16) The method of claim 16, wherein the gastric acid-inhibiting substance is administered in amounts of from 0.1 mg/kg to 100 mg/kg. ### Claim 20 (depends on 16) The method of claim 16, wherein the gastric acid-inhibiting substance is administered in an orally consumable preparation selected from the group consisting of capsules, tablets, sugar-coated pills, granules, pellets, mixtures of solids, emulsions, powders, and pastes. ### Claim 21 (depends on 16) The method of claim 16, wherein the gastric acid-stimulating component is caffeine. ### Claim 22 (depends on 16) The method of claim 16, wherein the gastric acid-stimulating component is theobromine. ### Claim 23 (depends on 16) The method of claim 16, wherein the gastric acid-inhibiting substance is administered in an orally consumable preparation which is in the form which causes delayed release. ### Claim 24 (depends on 16) The method of claim 16, wherein the gastric acid-stimulating component is present in a preparation selected from the group consisting of bakery products, confectionery, alcoholic or non-alcoholic drinks, meat products, eggs or egg products, cereal products, milk products, products made from soy protein or other soybean fractions, fruit preparations, vegetable preparations, snack foods, products based on fat and oil or emulsions of the same, other ready meals and soups, spices, spice mixtures and seasonings.