# US 2021/0330632 A1 · Methods for treating obesity > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0330632 A1 - Document ID: US20210330632A1 - Status: Published application - Kind: A1 - Application number: 17/371,838 - Filed: 2021-07-09 - Published: 2021-10-28 - Earliest claimed: 2015-08-10 - Assignees: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College - Applicants: Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College - Inventors: Hans-Rudolf Berthoud; Frank L. Greenway; Stefany DePrato Primeaux - Web page: https://patentgrep.com/patent/US20210330632A1 ## CPC - A61K 31/337: having four-membered rings, e.g. taxol - A61K 31/365: Lactones - A61K 36/185: Magnoliopsida (dicotyledons) - A61P 3/04: Anorexiants; Antiobesity agents - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract The present invention relates to methods of treating overweight or obesity, reducing fat, sugar, and food intake, and reducing body weight or body weight gain in a subject using geranium oil or orlistat mouthwash, or a combination of both. ## Claims ### Claim 1 A method for treating overweight or obesity in a subject in need thereof, comprising administering to the subject: a) a composition for oral administration comprising a therapeutically effective amount of geranium oil; and b) a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby treating overweight or obesity. ### Claim 2 A method for reducing body weight or body weight gain in a subject in need thereof, comprising administering to the subject: a) a composition for oral administration comprising a therapeutically effective amount of geranium oil; and b) a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby reducing body weight. ### Claim 3 A method for reducing food intake in a subject in need thereof, comprising administering to the subject: a) a composition for oral administration comprising a therapeutically effective amount of geranium oil; and b) a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby reducing food intake. ### Claim 4 A method for reducing dietary fat intake and/or dietary sugar intake in a subject in need thereof, comprising administering to the subject: a) a composition comprising a therapeutically effective amount of geranium oil; and b) a composition comprising a therapeutically effective amount of orlistat; thereby reducing dietary fat intake and/or dietary sugar intake. ### Claim 5 (depends on 1, 2, 3, 4) The method of any one of claims 1-4, wherein the geranium oil and orlistat are administered simultaneously or sequentially prior to consumption of a meal. ### Claim 6 (depends on 1, 2, 3, 4, 5) The method of any one of claims 1-5, wherein the geranium oil is administered in water soluble dry form. ### Claim 7 (depends on 1, 2, 3, 4, 5, 6) The method of any one of claims 1-6, wherein the geranium oil is administered at a dilution of about 1:100 to about 1:10,000. ### Claim 8 (depends on 1, 2, 3, 4, 5, 6, 7) The method of any one of claims 1-7, wherein the geranium oil is administered in an acid resistant capsule. ### Claim 9 (depends on 1, 2, 3, 4, 5, 6, 7, 8) The method of any one of claims 1-8, wherein the orlistat mouthwash contains about 1 mg to about 200 mg orlistat. ### Claim 10 A method for treating overweight or obesity in a subject in need thereof, comprising administering to the subject a composition for oral administration comprising a therapeutically effective amount of geranium oil, thereby treating overweight or obesity. ### Claim 11 A method for reducing body weight or body weight gain in a subject in need thereof, comprising administering to the subject a composition for oral administration comprising a therapeutically effective amount of geranium oil, thereby reducing body weight. ### Claim 12 A method for reducing food intake in a subject in need thereof, comprising administering to the subject a composition for oral administration comprising a therapeutically effective amount of geranium oil, thereby reducing food intake. ### Claim 13 A method for reducing dietary sugar intake in a subject in need thereof, comprising administering to the subject a composition for oral administration comprising a therapeutically effective amount of geranium oil, thereby reducing dietary sugar intake. ### Claim 14 (depends on 10, 11, 12, 13) The method of any one of claims 10-13, wherein the geranium oil is administered prior to a meal. ### Claim 15 (depends on 10, 11, 12, 13, 14) The method of any one of claims 10-14, wherein the geranium oil is administered in a water soluble dry form. ### Claim 16 (depends on 10, 11, 12, 13, 14, 15) The method of any one of claims 10-15, wherein the geranium oil is administered at a dilution of about 1:100 to about 1:10,000. ### Claim 17 (depends on 10, 11, 12, 13, 14, 15, 16) The method of any one of claims 10-16, wherein the geranium oil is administered in an acid resistant capsule. ### Claim 18 A method for treating overweight or obesity in a subject in need thereof, comprising administering to the subject a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby treating overweight or obesity. ### Claim 19 A method for reducing body weight or body weight gain in a subject in need thereof, comprising administering to the subject a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby reducing body weight. ### Claim 20 A method for reducing food intake in a subject in need thereof, comprising administering to the subject a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby reducing food intake. ### Claim 21 A method for reducing dietary fat intake in a subject in need thereof, comprising administering to the subject a mouthwash composition comprising a therapeutically effective amount of orlistat; thereby reducing dietary fat intake. ### Claim 22 (depends on 18, 19, 20, 21) The method of any one of claims 18-21, wherein the orlistat mouthwash is administered prior to a meal. ### Claim 23 (depends on 18, 19, 20, 21, 22) The method of any one of claims 18-22, wherein said orlistat mouthwash contains about 1 mg to about 200 mg orlistat. ### Claim 24 A composition for oral administration comprising geranium oil in an amount effective to treat overweight or obesity in a subject. ### Claim 25 (depends on 24) The composition of claim 24, wherein the geranium oil is in a water soluble dry form. ### Claim 26 (depends on 24, 25) The composition of claim 24 or 25, wherein the water soluble dry geranium oil is contained in an acid resistant capsule. ### Claim 27 (depends on 24, 25, 26) The composition of any one of claims 24-26, wherein the geranium oil is diluted about 1:100 to about 1:10,000. ### Claim 28 (depends on 24, 25, 26, 27) The composition of any one of claims 24-27, wherein said geranium oil is contained in an acid resistant capsule. ### Claim 29 A mouthwash composition comprising orlistat in an amount effective to treat overweight or obesity in a subject. ### Claim 30 (depends on 29) The composition of claim 29, wherein said orlistat mouthwash contains about 1 mg to about 200 mg orlistat. ### Claim 31 (depends on 24, 25, 26, 27, 28, 29, 30) A combination comprising: a) the geranium oil of any one of claims 24-28; and b) the orlistat of any one of claims 29-30. ### Claim 32 (depends on 24, 25, 26, 27, 28, 29, 30) A kit comprising: a) the geranium oil of any one of claims 24-28; and b) the orlistat of any one of claims 29-30.