# US 2021/0330606 A1 · Glucose consumption accelerator and glycolysis accelerator

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- Number: US 2021/0330606 A1
- Document ID: US20210330606A1
- Status: Published application
- Kind: A1
- Application number: 16/610,360
- Filed: 2019-05-27
- Published: 2021-10-28
- Earliest claimed: 2018-07-31
- Assignees: Kenji SORIMACHI; Shinko Sangyo Co. Ltd.
- Applicants: SHINKO SANGYO Co., Ltd.
- Inventors: Kenji SORIMACHI
- Web page: https://patentgrep.com/patent/US20210330606A1

## CPC

- A61K 31/133: having hydroxy groups, e.g. sphingosine
- A61P 3/08: for glucose homeostasis (pancreatic hormones A61P5/48)
- A61K 9/0053: {Mouth and digestive tract, i.e. intraoral and peroral administration}
- A61K 31/13: Amines {(A61K31/04 takes precedence)}
- A61K 31/131: acyclic
- A61K 31/136: having the amino group directly attached to the aromatic ring, e.g. benzeneamine
- A61K 31/137: Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine {or methadone}
- A61K 31/535: having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K 31/5375: 1,4-Oxazines, e.g. morpholine
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention provides a new drug that can accelerate glucose consumption. The glucose consumption accelerator of the present invention includes: at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane.

## Claims

### Claim at position 1

1-4. (canceled)

### Claim 5

A glucose consumption accelerating method, comprising the step of:
administering a glucose consumption accelerator comprising at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane.

### Claim at position 3

6-9. (canceled)

### Claim 10

A glycolysis accelerating method comprising the step of:
administering a glycolysis accelerator comprising at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane.

### Claim 11 (depends on 5)

The glucose consumption accelerating method according to claim 5, comprising the step of:
administering the glucose consumption accelerator comprising at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane as a main component.

### Claim 12 (depends on 5)

The glucose consumption accelerating method according to claim 5, wherein
the glucose consumption accelerator further comprising:
an oral additive.

### Claim 13 (depends on 5)

A treatment method of diabetes comprising the administering step in the glucose consumption accelerating method according to claim 5.

### Claim 14 (depends on 10)

The glycolysis accelerating method according to claim 10, comprising the step of:
administering the glycolysis accelerator comprising at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane as a main component.

### Claim 15 (depends on 10)

The glycolysis accelerating method according to claim 10, wherein
the glycolysis accelerator further comprising:
an oral additive.

### Claim 16 (depends on 10)

A treatment method of diabetes comprising the administering step in the glycolysis accelerating method according to claim 10.