# US 2021/0330307 A1 · Vascular hole closure device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0330307 A1 - Document ID: US20210330307A1 - Status: Published application - Kind: A1 - Application number: 17/372,451 - Filed: 2021-07-10 - Published: 2021-10-28 - Earliest claimed: 2008-02-15 - Assignees: Rex Medical, L.P. - Applicants: Rex Medical, L.P. - Inventors: James F. McGuckin, JR.; John D. Leedle; James S. Tarmin; Thanu Anidharan; Stephan A. DeFonzo - Web page: https://patentgrep.com/patent/US20210330307A1 ## CPC - A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)} - A61B 17/0401: {Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors (A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811)} - A61B 2017/00004: {(bio)absorbable, (bio)resorbable or resorptive} - A61B 2017/00615: {Implements with an occluder on one side of the opening and holding means therefor on the other} - A61B 2017/00659: {located only on one side of the opening} - A61B 2017/00778: {Operations on blood vessels (A61B2017/22097, A61B2017/320741 take precedence)} - A61B 2017/0404: {Buttons} - A61B 2017/0456: {Surface features on the anchor, e.g. ribs increasing friction between the suture and the anchor} - A61B 2017/0459: {Multiple holes in the anchor through which the suture extends and locking the suture when tension is applied} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A device for closing an aperture in a vessel wall comprising a covering member having a longitudinal axis and positionable inside the vessel against the internal opening of the aperture and having a dimension to prevent egress of fluid through the aperture and having a first opening. A first retainer is positionable external of the vessel. A flexible connecting member operatively connects the covering member and the first retainer, wherein the first opening of the covering member is configured to restrict movement of the connecting member. ## Claims ### Claim at position 1 1-20. (canceled) ### Claim 21 A hole closure device for closing an aperture in a vessel wall, the aperture having an external opening in an external region of the vessel wall and an internal opening in an internal region of the vessel wall, the hole closure device comprising: a first member having a first width in a delivery position and in a placement position; a second member; and a flexible connecting member operatively connecting the first member and the second member, the first member secured to the flexible connecting member, wherein the flexible connecting member advances the first member toward the second member, wherein movement of the flexible connecting member in a proximal direction advances the first member toward the second member in a distal direction for placement of the first member in the placement position, the flexible connecting member being restricted from movement and retained in a fixed position by the hole closure device until a sufficient predetermined proximal force is applied to the flexible connecting member to override a restriction force and free it from being restricted. ### Claim 22 (depends on 21) The device of claim 21, wherein the flexible connecting member comprises a first suture. ### Claim 23 (depends on 21) The device of claim 21, wherein the flexible connecting member is restricted by a first opening in the second member. ### Claim 24 (depends on 23) The device of claim 23, wherein the first opening has a configuration to frictionally engage the flexible connecting member. ### Claim 25 (depends on 21) The device of claim 21, wherein the flexible connecting member has a first end secured to the first member and a second end not secured to the first member. ### Claim 26 (depends on 23) The device of claim 23, wherein the second member has a second opening larger than the first opening, the second opening non-contiguous with the first opening. ### Claim 27 (depends on 25) The device of claim 25, wherein the second member has a second opening larger than the first opening, the second opening non-contiguous with the first opening. ### Claim 28 (depends on 21) The device of claim 21, wherein the first member, second member and flexible connecting member are composed of a resorbable material. ### Claim 29 (depends on 27) The device of claim 27, wherein the second opening allows unrestricted movement of the flexible connecting member. ### Claim 30 (depends on 29) The device of claim 29, wherein the flexible connecting member loops through the first and second openings. ### Claim 31 (depends on 21) The device of claim 21, wherein the second member is pivotable between a more longitudinal orientation for delivery and a transverse position for placement. ### Claim 32 A hole closure device for closing an aperture in a vessel wall, the aperture having an external opening in an external region of the vessel wall and an internal opening in an internal region of the vessel wall, the hole closure device comprising: a first member; a second member; and a flexible connecting member operatively connecting the first member and the second member, the first member secured to the flexible connecting member, wherein the flexible connecting member advances the first member toward the second member, wherein the flexible connecting member is restricted in movement by engagement of any one of a plurality of contiguous regions along its length by the closure device, the flexible connecting member is freed from its restriction of movement upon application of a sufficient proximal force to a first end of the flexible connecting member, and is restricted by engagement of one of the plurality of regions along its length when the application of sufficient force ceases, the application of sufficient proximal force pulls the end of the flexible connecting member proximally. ### Claim 33 (depends on 32) The device of claim 32, wherein the flexible connecting member has a second end and an intermediate portion positioned between the first end and the second end, and the intermediate portion loops through the second member. ### Claim 34 (depends on 33) The device of claim 33, wherein the flexible connecting member loops through first and second openings in the second member. ### Claim 35 (depends on 32) The device of claim 32, wherein movement of the flexible connecting member is restricted within an opening in the second member. ### Claim 36 (depends on 35) The device of claim 35, wherein the opening has a configuration to frictionally engage the connecting member. ### Claim 37 (depends on 36) The device of claim 36, wherein the second member has a second opening to allow unrestricted movement of the connecting member. ### Claim 38 (depends on 32) The device of claim 32, wherein the flexible connecting member has a uniform diameter at the plurality of contiguous regions engageable with the second member. ### Claim 39 (depends on 37) The device of claim 37, wherein the first and second openings extend through a top surface and a bottom surface of the second member.