# US 2021/0330262 A1 · Bioinformatics sensor patch

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- Number: US 2021/0330262 A1
- Document ID: US20210330262A1
- Status: Published application
- Kind: A1
- Application number: 17/236,547
- Filed: 2021-04-21
- Published: 2021-10-28
- Earliest claimed: 2020-04-23
- Assignees: Seknova Biotechnology Co., Ltd.
- Applicants: Seknova Biotechnology Co., Ltd.
- Inventors: CHING CHUN HUANG; SHIH HSUAN KU; YI JEN CHEN; PING CHUN WANG
- Web page: https://patentgrep.com/patent/US20210330262A1

## CPC

- A61B 5/6833: {Adhesive patches}
- A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20)
- A61B 5/14503: {invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence)}
- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes}
- A61B 5/1486: using enzyme electrodes, e.g. with immobilised oxidase
- A61B 5/6844: {Monitoring or controlling distance between sensor and tissue}
- A61B 5/7405: {using sound}
- A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)}
- A61B 5/7455: {characterised by tactile indication, e.g. vibration or electrical stimulation}
- A61B 2560/0252: using ambient temperature
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A bioinformatics sensor patch includes a plurality of sensing electrodes, a distance sensing element and an operation unit. The sensing electrodes senses bioinformatics of an organism. The distance sensing element senses a contact degree between the bioinformatics sensor patch and the organism and generates a corresponding contact signal. The operation unit is electrically connected to the sensing electrodes and the distance sensing element to receive the bioinformatics and the contact signal, wherein the operation unit compensates the bioinformatics or selectively outputs a control signal according to the contact signal. The above-mentioned bioinformatics sensor patch can improve a sensing accuracy of the bioinformatics.

## Claims

### Claim 1

A bioinformatics sensor patch, comprising:
a plurality of sensing electrodes, configured to contact an organism and sense bioinformatics of the organism;
a distance sensing element, configured to sense a contact degree between the bioinformatics sensor patch and the organism and generate a corresponding contact signal; and
an operation unit, electrically connected with the plurality of sensing electrodes and the distance sensing element to receive the bioinformatics and the contact signal, executing at least one of actions of compensating the bioinformatics and selectively outputting a control signal according to the contact signal.

### Claim 2 (depends on 1)

The bioinformatics sensor patch according to claim 1, further comprising:
a reminder unit, electrically connected with the operation unit, and generating a reminding signal recognizable by a user according to the control signal output by the operation unit.

### Claim 3 (depends on 2)

The bioinformatics sensor patch according to claim 2, wherein the reminder unit includes a display, a light, a buzzer, a vibration motor, or a communication interface.

### Claim 4 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the operation unit performs a bioinformatics compensation method, which includes:
working out a first compensation parameter according to the contact signal; and
processing the bioinformatics according to the first compensation parameter to acquire first compensation bioinformatics.

### Claim 5 (depends on 1)

The bioinformatics sensor patch according to claim 1, further comprising:
a first temperature sensor, electrically connected with the operation unit, and configured to sense an ambient temperature of the bioinformatics sensor patch, wherein the operation unit performs compensation to the bioinformatics or selectively outputs the control signal according to the ambient temperature.

### Claim 6 (depends on 5)

The bioinformatics sensor patch according to claim 5, wherein the operation unit performs a bioinformatics compensation method, which includes:
working out a first compensation parameter according to the contact signal;
processing the bioinformatics according to the first compensation parameter to acquire first compensation bioinformatics;
working out a second compensation parameter according to the ambient temperature; and
processing the first compensation bioinformatics according to the second compensation parameter to acquire second compensation bioinformatics.

### Claim 7 (depends on 1)

The bioinformatics sensor patch according to claim 1, further comprising:
a second temperature sensing electrode, electrically connected with the operation unit, and configured to sense a body temperature of the organism, wherein the operation unit performs compensation to the bioinformatics or selectively outputs the control signal according to the body temperature.

### Claim 8 (depends on 7)

The bioinformatics sensor patch according to claim 7, wherein the operation unit performs a bioinformatics compensation method, which includes:
working out a first compensation parameter according to the contact signal;
processing the bioinformatics according to the first compensation parameter to acquire first compensation bioinformatics;
working out a third compensation parameter according to the body temperature of the organism; and
processing the first compensation bioinformatics according to the third compensation parameter to acquire third compensation bioinformatics.

### Claim 9 (depends on 1)

The bioinformatics sensor patch according to claim 1, further comprising:
a first temperature sensor, electrically connected with the operation unit, and configured to sense an ambient temperature of the bioinformatics sensor patch; and
a second temperature sensing electrode, electrically connected with the operation unit, and configured to sense a body temperature of the organism, wherein the operation unit performs compensation to the bioinformatics or selectively outputs the control signal according to the ambient temperature and the body temperature.

### Claim 10 (depends on 9)

The bioinformatics sensor patch according to claim 9, wherein the operation unit performs a bioinformatics compensation method, which includes:
working out a first compensation parameter according to the contact signal;
processing the bioinformatics according to the first compensation parameter to acquire first compensation bioinformatics;
working out a second compensation parameter and a third compensation parameter respectively according to the ambient temperature and the body temperature; and
processing the first compensation bioinformatics according to the second compensation parameter and the third compensation parameter to acquire fourth compensation bioinformatics.

### Claim 11 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the distance sensing element senses the contact degree between the bioinformatics sensor patch and the organism according to variation of resistance, capacitance, or voltage.

### Claim 12 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the sensing electrode is made of an electric-conduction material including at least one of graphene, carbon, gold, silver, stainless steel, nickel, nickel alloys, titanium, and titanium alloys.

### Claim 13 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein a sensing terminal of the sensing electrode is in form of a sharp needle, a convex point or a plane.

### Claim 14 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the plurality of sensing electrodes includes at least one reference electrode, at least one working electrode and at least one counter electrode.

### Claim 15 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the plurality of sensing electrodes includes at least one reference electrode and a plurality of working electrodes.

### Claim 16 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the plurality of sensing electrodes includes at least one reference electrode and a plurality of working electrodes, and surfaces of the plurality of working electrodes are coated with different sensing layers.

### Claim 17 (depends on 1)

The bioinformatics sensor patch according to claim 1, wherein the bioinformatics includes at least one of concentrations of blood glucose, blood ketone, lactic acid, an antibody, and a drug.
