# US 2021/0330221 A1 · Analyte sensor

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- Number: US 2021/0330221 A1
- Document ID: US20210330221A1
- Status: Published application
- Kind: A1
- Application number: 17/370,095
- Filed: 2021-07-08
- Published: 2021-10-28
- Earliest claimed: 2015-02-24
- Assignees: Senseonics, Incorporated
- Applicants: Senseonics, Incorporated
- Inventors: Andrew DeHennis; Szymon Tankiewicz; Todd Whitehurst
- Web page: https://patentgrep.com/patent/US20210330221A1

## CPC

- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61B 5/0002: {Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network (endoradiosondes A61B5/07)}
- A61B 5/0075: {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence)}
- A61B 5/1459: invasive, e.g. introduced into the body by a catheter
- A61B 2560/0214: of power generation or supply
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Sensors and methods for measurement of an analyte in a medium within a living animal are described. The sensor may include an inductive element that may receive power from an external device. The sensor may also include a charge storage device (CSD) and a memory. The sensor may perform analyte measurements initiated by the external device using power received from the external device and convey the analyte measurements to the external device using the inductive element. The sensor also may perform autonomous analyte measurements using the on board charge device's power and store the autonomous analyte measurements in the memory. The sensor may convey one or more stored analyte measurements to the external device using the inductive element using power received from the external device. The sensor may include a CSD-powered clock and a CSD-powered measurement scheduler that initiate the autonomous analyte measurements.

## Claims

### Claim 1

A sensor comprising:
an analyte indicator configured to exhibit a detectable property based on an amount or concentration of an analyte in a medium within a living animal;
one or more sensor elements configured to generate an analyte measurement signal based on the detectable property exhibited by the analyte indicator;
an input/output circuit configured to wirelessly convey measurement information to an external device;
a measurement controller;
a charge storage device;
a clock that is powered by the charge storage device; and
a measurement scheduler that is powered by the charge storage device and configured to use an output of the clock to periodically determine that an interval of time has passed,
wherein the measurement controller is configured to:
(i) if the measurement scheduler has determined that the interval of time has passed, control the one or more sensor elements to generate the analyte measurement signal using power provided by the charge storage device;
(ii) generate measurement information based on the analyte measurement signal; and
(iii) control the input/output circuit to wirelessly convey the measurement information to the external device.

### Claim 2 (depends on 1)

The sensor of claim 1, wherein the detectable property exhibited by the analyte indicator is an optical characteristic responsive to the amount or concentration of the analyte in the medium, the one or more sensor elements comprise one or more light sources and one or more photodetectors, and the analyte measurement signal is a light measurement signal.

### Claim 3 (depends on 1)

The sensor of claim 1, wherein the measurement information comprises the analyte measurement signal.

### Claim 4 (depends on 3)

The sensor of claim 3, wherein one or more sensor elements comprise a temperature transducer, and the measurement information further comprises a temperature measurement signal indicative of a temperature of the sensor.

### Claim 5 (depends on 3)

The sensor of claim 3, wherein the measurement information further comprises a time-stamp identifying a time at which the measurement information was generated.

### Claim 6 (depends on 1)

The sensor of claim 1, wherein the sensor is implantable within the living animal.

### Claim 7 (depends on 6)

The sensor of claim 6, wherein the sensor is fully implantable within the living animal.

### Claim 8 (depends on 1)

The sensor of claim 1, wherein the measurement scheduler is configured to issue an autonomous measurement command each time the measurement scheduler determines that the interval of time has passed.

### Claim 9 (depends on 8)

The sensor of claim 8, further comprising a command decoder configured to decode and/or send the autonomous measurement command to the measurement controller.

### Claim 10 (depends on 1)

The sensor of claim 1, further comprising a power switch configured to switch one or more of the sensor elements, the input/output circuit, and the measurement controller from being powered by an externally supplied electrodynamic field to being powered by the charge storage device if the measurement scheduler has determined that the interval of time has passed.

### Claim 11 (depends on 1)

The sensor of claim 1, further comprising a non-volatile storage medium, wherein the measurement controller is further configured to:
store the measurement information in the non-volatile storage medium; and
retrieve the measurement information from the non-volatile storage medium.

### Claim 12 (depends on 11)

The sensor of claim 11, wherein the measurement information is first measurement information, the measurement controller is further configured to retrieve second measurement information from the non-volatile storage medium, and the measurement controller is configured to control the input/output circuit to wirelessly convey the first and second measurement information to the external device.

### Claim 13

A method comprising:
using a charge storage device of a sensor to power a measurement controller and a clock of the sensor;
using the measurement scheduler to periodically determine that an interval of time has passed, wherein the measurement scheduler uses an output of the clock to periodically determine that the interval of time has passed;
if the measurement scheduler has determined that the interval of time has passed, using a measurement controller of the sensor to control one or more sensor elements of the sensor to generate an analyte measurement signal using power provided by the charge storage device, wherein the analyte measurement signal is based on a detectable property exhibited by an analyte indicator of the sensor, and the analyte indicator exhibits the detectable property based on an amount or concentration of an analyte in a medium within a living animal;
using the measurement controller to generate measurement information based on the analyte measurement signal; and
using the measurement controller to control an input/output circuit of the sensor to wirelessly convey the measurement information to an external device.

### Claim 14 (depends on 13)

The method of claim 13, wherein the detectable property exhibited by the analyte indicator is an optical characteristic responsive to the amount or concentration of the analyte in the medium, the one or more sensor elements comprise one or more light sources and one or more photodetectors, and the analyte measurement signal is a light measurement signal.

### Claim 15 (depends on 13)

The method of claim 13, wherein the measurement information comprises the analyte measurement signal.

### Claim 16 (depends on 15)

The method of claim 15, wherein one or more sensor elements comprise a temperature transducer, and the measurement information further comprises a temperature measurement signal indicative of a temperature of the sensor.

### Claim 17 (depends on 15)

The method of claim 15, wherein the measurement information further comprises a time-stamp identifying a time at which the measurement information was generated.

### Claim 18 (depends on 13)

The method of claim 13, wherein the sensor is implantable within the living animal.

### Claim 19 (depends on 18)

The method of claim 18, wherein the sensor is fully implantable within the living animal.

### Claim 20 (depends on 13)

The method of claim 13, further comprising using the measurement scheduler to issue an autonomous measurement command each time the measurement scheduler determines that the interval of time has passed.

### Claim 21 (depends on 20)

The method of claim 20, further comprising using a command decoder of the sensor to decode and/or send the autonomous measurement command to the measurement controller.

### Claim 22 (depends on 13)

The method of claim 13, further comprising using a power switch to switch one or more of the sensor elements, the input/output circuit, and the measurement controller from being powered by an externally supplied electrodynamic field to being powered by the charge storage device if the measurement scheduler has determined that the interval of time has passed.

### Claim 23 (depends on 13)

The method of claim 13, further comprising:
using the measurement controller to store the measurement information in a non-volatile storage medium of the sensor;
using the measurement controller to retrieve the first measurement information and second measurement information from the non-volatile storage medium; and
using the measurement controller to control an input/output circuit of the sensor to wirelessly convey the measurement information to an external device.

### Claim 24 (depends on 23)

The method of claim 23, wherein the measurement information is first measurement information, the method further comprises using the measurement controller to retrieve second measurement information from the non-volatile storage medium, and using the measurement controller to control the input/output circuit to wirelessly convey the first and second measurement information to the external device.
