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US 2021/0322324 A1Published application
Method for treating primary sclerosing cholangitis
AssigneeAvolynt
InventorsWilliam Owen WILKISON, James Trinca GREEN
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Abstract
The invention relates to the use of pharmaceutical compositions of the SGLT2 inhibitor, remogliflozin etabonate, to treat primary sclerosing cholangitis (PSC). Methods and compositions associated with the invention can improve or maintain clinical outcomes of PSC symptoms, such as ascites accumulation, hepatic encephalopathy, development of varices, jaundice, variceal bleeding, cholangiocarcinoma, hepatocellular carcinoma, evidence of cirrhosis, and colorectal cancer.
Claims15
A method for treating primary sclerosing cholangitis (PSC), comprising administering remogliflozin etabonate, or a salt thereof.
Dependencies are inferred from the claim text.