Method of preparing primary amines from amino acids using enzymatic conversion
AssigneeKorea Advanced Institute of Science and Technology
InventorsSang Yup LEE, Dong In KIM, Tong Un CHAE
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Abstract
Disclosed is a method of preparing primary amines. More particularly, disclosed are a mutant microorganism transformed with a gene encoding a valine decarboxylase and a method of preparing primary amines from amino acids using the mutant microorganism. The method has an effect of synthesizing, in an environmentally friendly manner, primary amines as precursors for pharmaceuticals and agricultural chemicals using microorganisms, as an alternative to conventional chemical synthesis methods.
Claims12
A mutant microorganism capable of producing a primary amine from an amino acid, in which a gene encoding a valine decarboxylase is introduced into the mutant microorganism.
A method of preparing a primary amine comprising:
- (a) reacting a valine decarboxylase with an amino acid to produce a primary amine;
- and
- (b) collecting the produced primary amine.
Dependencies are inferred from the claim text.