Compositions acting as pro(renin) receptor antagonists for the treatment of non-alcoholic fatty liver disease
AssigneeBoard of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno
InventorYumei Feng EARLEY
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Abstract
Disclosed are methods of treating metabolic diseases, such as non-alcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), and Type II diabetes. In some examples, the method includes administration of an effective amount of a (pro)renin receptor (PRR) antagonist to a subject in need thereof, such as a patient at risk of acquiring or afflicted with NAFLD, NASH and/or Type II diabetes, to prevent, inhibit, and/or reduce one or more signs or symptoms associated with NAFLD, NASH and/or Type II diabetes, such as by reducing the severity of liver steatosis.
Claims19
A method of treating, comprising administering to a subject at risk of acquiring or afflicted with non-alcoholic fatty liver disease (NAFLD) an effective amount of a composition comprising a (pro)renin receptor (PRR) antagonist.
Dependencies are inferred from the claim text.