Methods for determining gene-alpha tocopherol interactions
AssigneeBodysync, Inc.
InventorsRosalynn D. Gill, Robert F. Grimble
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Abstract
Method for predicting the change in the level of at least one pro-inflammatory cytokine in an individual due to alpha tocopherol supplementation are provided, as well as methods for predicting the response of an individual to alpha tocopherol supplementation, and methods of nutrigenetic screening of an individual.
Claims12
A method for predicting the change in the level of at least one pro-inflammatory cytokine in an individual due to alpha tocopherol supplementation, the method comprising:
- analyzing a sample obtained from the human for the presence of one or more genetic variations in at least one gene correlated with a change in serum pro-inflammatory cytokine levels;
- detecting the genotype of the at least one gene correlated with a with a change in serum pro-inflammatory cytokine levels;
- and
- predicting an outcome of the change based on the correlation.
A method for predicting the response of an individual to alpha tocopherol supplementation, which method comprises:
- determining the GSTP1 genotype at position 313;
- and
- predicting a greater response to said alpha tocopherol supplementation when the individual is homozygous at the G allele at position 313 than when the individual has another genotype at position 313.
In a method of nutrigenetic screening of an individual, the improvement comprising:
- determining whether the individual has a GG genotype at position 313 of the GSTP1 gene;
- and;
- recommending a minimum level of vitamin E intake in the diet to the individual where the GG genotype is present.
Dependencies are inferred from the claim text.