Loading patent…
AssigneeThe University of Western Australia
InventorsTimothy John Jay Inglis, Kieran Mulroney, Jarrad Hall
Estimating the term…
The present invention relates to methods for the qualitative and quantitative determination of the susceptibility of microbial organisms such as bacteria to antimicrobial agents such as antibiotics. For example, the present invention provides a method of determining the susceptibility of a unicellular or multicellular microorganism to an antimicrobial agent by acoustic flow cytometry. The method comprising exposing cells of the microorganism to at least one antimicrobial agent, wherein said cells of the microorganism are in and/or derived from a sample obtained from a subject having or suspected of having an infection with said microorganism; measuring effect of said at least one antimicrobial agent on cellular morphology of said cells of the microorganism by acoustic flow cytometry; and determining susceptibility of the microorganism to the at least one antimicrobial agent from the acoustic flow cytometry data output.
A method of determining the susceptibility of a unicellular or multicellular microorganism to an antimicrobial agent by acoustic flow cytometry, said method comprising:
The method of any one of claims 41 to 45, comprising:
The method of any 76, comprising incubating the cells of the microorganism for a time and under conditions sufficient for the cells to undergo about 1 to about 3 cell divisions.
Dependencies are inferred from the claim text.