US 2021/0282968 A1 · AUTOMATED CALIBRATION OF LASER SYSTEM AND TOMOGRAPHY SYSTEM WITH FLUORESCENT IMAGING OF SCAN PATTERN

Abstract

A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.

Claims22

Dependent claims

A method of calibrating a laser system with a treatment space, the method comprising:

calibrating a camera of the laser system to provide a mapping of pixel locations of pixels of the camera to a treatment space of the laser system, including viewing, using the camera, a calibration plate positioned relative to the camera at a known distance, the calibration plate defining discrete known locations in the treatment space;
scanning an electromagnetic radiation beam of the laser system to a series of scanning locations of a material disposed in the treatment space using a scanning system of the laser system by moving the electromagnetic radiation beam relative to a propagation direction of the electromagnetic radiation beam;
capturing, using the camera, a light from the series of locations of the material in response to the scanned electromagnetic radiation beam, the captured series of locations corresponding to a series of measured pixel locations of the camera;
and
calibrating the scanning system with the treatment space per the series of measured pixel locations and the mapping of the camera pixel locations to the treatment space.

2 more elements

A laser system, comprising:

an electromagnetic radiation beam source configured to output a beam along a beam path toward a treatment space;
a scanning system disposed along the beam path, the scanning system configured to direct the outputted beam to a plurality of locations in the treatment space;
a camera having a plurality of pixels and configured to capture images of the treatment space;
and
a processor coupled with the scanning system and the camera, the processor configured to calibrate the scanning system by:
calibrating the camera to provide a mapping of pixel locations of the camera pixels to the treatment space, including viewing, using the camera, a calibration plate positioned relative to the camera at a known distance, the calibration plate defining discrete known locations in the treatment space;
scanning the electromagnetic radiation beam of the laser system orthogonally to a propagation direction of the electromagnetic radiation beam between a series of scanning locations of a material disposed in the treatment space using the scanning system;
capturing, using the camera, a light from the series of locations of the material in response to the scanned electromagnetic radiation beam, the captured series of locations corresponding to a series of measured pixel locations of the camera;
and
calibrating the scanning system with the treatment space per the series of measured pixel locations and the mapping of the camera pixel locations to the treatment space.

7 more elements

Dependencies are inferred from the claim text.

Automated calibration of laser system and tomography system with fluorescent imaging of scan pattern

Life of this patent

Automated calibration of laser system and tomography system with fluorescent imaging of scan pattern

Life of this patent

Abstract

Claims22