# US 2021/0277250 A1 · Aminocoumarin compound, and aminocoumarin compound-containing resin particles

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- Number: US 2021/0277250 A1
- Document ID: US20210277250A1
- Status: Published application
- Kind: A1
- Application number: 16/477,433
- Filed: 2018-02-13
- Published: 2021-09-09
- Earliest claimed: 2017-02-14
- Assignees: Konica Minato, Inc.
- Applicants: Konica Minato, Inc.
- Inventors: Kensaku TAKANASHI; Shin NAKAYAMA; Kenji NISHIKAWA; Takeshi ISODA
- Web page: https://patentgrep.com/patent/US20210277250A1

## CPC

- C09B 57/02: Coumarine dyes
- C08K 5/1545: Six-membered rings
- C09B 67/009: {polymeric dispersing agent}
- C09B 67/0097: {Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes}
- C09B 69/00: Dyes not provided for by a single group of this subclass
- C09B 69/109: {containing other specific dyes}
- C09K 11/06: containing organic luminescent materials
- G01N 33/533: with fluorescent label
- C09B: ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES {, e.g. PIGMENTS}; MORDANTS; LAKES (fermentation or enzyme using processes to synthesise a desired chemical compound C12P)
- C08K: Use of inorganic or non-macromolecular organic substances as compounding ingredients (paints, inks, varnishes, dyes, polishes, adhesives C09)
- C09K: MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

The present invention provides: an aminocoumarin compound having a structure represented by the following formula (1); and an aminocoumarin compound-containing resin particle containing the aminocoumarin compound and a resin particle containing the aminocoumarin compound. In formula (1), Rs each independently represent a hydrogen atom or a methyl group, Q represents a sulfur atom, an oxygen atom, or N—R1, and R1 represents a hydrogen atom or a methyl group. The aminocoumarin compound of the present invention is a fluorescent dye that has a longer excitation wavelength than a conventionally known sulfonated coumarin-based compound and is effectively excited at a wavelength of 475 nm or more, particularly at a wavelength around 500 nm. The aminocoumarin compound of the present invention is a fluorescent dye that is excited, for example, at a wavelength of 475 to 510 nm and can be observed in a green light emission region of 510 to 540 nm using the wavelength characteristic, and can be expected to be suitably utilized in immunostaining or the like.

## Claims

### Claim 1

An aminocoumarin compound having a structure represented by the following formula (1):
wherein Rs each independently represent a hydrogen atom or a methyl group, Q represents a sulfur atom, an oxygen atom, or N—R1, and R1 represents a hydrogen atom or a methyl group.

### Claim 2 (depends on 1)

The aminocoumarin compound according to claim 1, wherein Q in the formula (1) is a sulfur atom.

### Claim 3 (depends on 1)

The aminocoumarin compound according to claim 1, wherein Q in the formula (1) is an oxygen atom.

### Claim 4 (depends on 1)

The aminocoumarin compound according to claim 1, wherein Q in the formula (1) is N—R1.

### Claim 5 (depends on 1)

An aminocoumarin compound-containing resin particle comprising the aminocoumarin compound according to claim 1 and a resin particle containing the aminocoumarin compound.

### Claim 6 (depends on 5)

The aminocoumarin compound-containing resin particle according to claim 5, wherein the resin particle is an amino resin particle.

### Claim 7 (depends on 5)

The aminocoumarin compound-containing resin particle according to claim 5, having an excitation spectrum maximum wavelength of 475 to 510 nm and a fluorescence spectrum maximum wavelength of 510 to 540 nm.

### Claim 8 (depends on 6)

The aminocoumarin compound-containing resin particle according to claim 6, having an excitation spectrum maximum wavelength of 475 to 510 nm and a fluorescence spectrum maximum wavelength of 510 to 540 nm.