# US 2021/0276084 A1 · Nanoparticle self-assembling method for forming core-shell nanohybrids

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- Number: US 2021/0276084 A1
- Document ID: US20210276084A1
- Status: Published application
- Kind: A1
- Application number: 17/163,071
- Filed: 2021-01-29
- Published: 2021-09-09
- Earliest claimed: 2020-03-06
- Assignees: Florida Atlantic University Board of Trustees
- Applicants: Florida Atlantic University Board of Trustees
- Inventors: Peng YI; Kazi Albab HUSSAIN
- Web page: https://patentgrep.com/patent/US20210276084A1

## CPC

- H01F 1/0054: {Coated nanoparticles, e.g. nanoparticles coated with organic surfactant}
- B22F 1/054: Nanosized particles
- B22F 1/0545: Dispersions or suspensions of nanosized particles
- B22F 1/102: Metallic powder coated with organic material
- B22F 1/16: Metallic particles coated with a non-metal (coated with lubricating or binding agents or with organic material B22F1/10)
- C01G 49/06: Ferric oxide [Fe2O3]
- C08F 212/08: Styrene
- B22F 2301/35: Iron
- B22F 2303/20: Coating by means of particles
- B22F 2304/05: Submicron size particles
- B82Y 25/00: Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
- B82Y 30/00: Nanotechnology for materials or surface science, e.g. nanocomposites
- B82Y 40/00: Manufacture or treatment of nanostructures
- C01P 2004/04: obtained by TEM, STEM, STM or AFM
- C01P 2004/64: Nanometer sized, i.e. from 1-100 nanometer
- C01P 2004/80: Particles consisting of a mixture of two or more inorganic phases
- C08L 25/18: Homopolymers or copolymers of aromatic monomers containing elements other than carbon and hydrogen
- C09C 1/24: Oxides of iron
- C09C 3/10: Treatment with macromolecular organic compounds {(C09C3/006 takes precedence)}
- H01F: MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- B22F: WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER (making alloys by powder metallurgy C22C); APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- C01G: COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F (metal hydrides {monoborane, diborane or addition complexes thereof} C01B6/00; salts of oxyacids of halogens C01B11/00; peroxides, salts or peroxyacids C01B15/00; thiosulfates, dithionites, polythionates C01B17/64; compounds containing selenium, or tellurium C01B19/00; binary compounds of nitrogen with metals C01B21/06; azides C01B21/08; {compounds containing nitrogen, other non-metals and metal C01B21/082}; metal amides C01B21/092; nitrites C01B21/50; {compounds of noble gases C01B23/0005}; phosphides C01B25/08; salts of oxyacids of phosphorus C01B25/16; carbides C01B32/90; compounds containing silicon C01B33/00; compounds containing boron C01B35/00; compounds having molecular sieve properties but not having base-exchange properties C01B37/00; compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites, C01B39/00; cyanides C01C3/08; salts of cyanamide C01C3/16; thiocyanates C01C3/20)
- C08F: MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- B82Y: SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- C01P: INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06)
- C09C: TREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES (treatment of materials specially adapted to enhance their filling properties in mortars, concrete or artificial stone C04B14/00, C04B18/00, C04B20/00); PREPARATION OF CARBON BLACK {; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS}

## Abstract

A method of synthesizing core-shell nanohybrids is described herein. The method includes providing first nanoparticles and second nanoparticles in a liquid medium at a pH at which the first nanoparticles are neutral and the second nanoparticles are negatively charged, allowing the first nanoparticles to homoaggregate and form a core of at least one of the first nanoparticles, and allowing the second nanoparticles to heteroaggregate with the homoaggregated first nanoparticles to form a shell on the core so as to provide the core-shell nanohybrids. A nanohybrid is additionally described herein, which includes a core including at least one neutral nanoparticle within a shell containing charged nanoparticles, wherein the shell further includes nanogaps configured to allow access of substrates to the core.

## Claims

### Claim 1

A method of forming core-shell nanohybrids, said method comprising:
providing first nanoparticles and second nanoparticles in a liquid medium at a pH at which the first nanoparticles are neutral and the second nanoparticles are negatively or positively charged;
allowing the first nanoparticles to homoaggregate;
forming a core of at least one of the first nanoparticles; and
allowing the second nanoparticles to heteroaggregate with the homoaggregated first nanoparticles to form a shell on the core so as to provide the core-shell nanohybrids.

### Claim 2 (depends on 1)

The method of claim 1, which is conducted at a temperature of 20-25° C.

### Claim 3 (depends on 1)

The method of claim 1, which is conducted without organic reducing agents, organic solvents, organic ligands, or organic surfactants.

### Claim 4 (depends on 3)

The method of claim 3, which is conducted without stirring.

### Claim 5 (depends on 1)

The method of claim 1, wherein a base or an acid is added to the liquid medium to adjust the pH of the liquid medium to a pH point of zero charge of the first nanoparticles.

### Claim 6 (depends on 5)

The method of claim 5, wherein the liquid medium is an aqueous solution.

### Claim 7 (depends on 1)

The method of claim 1, wherein the first nanoparticles and the second nanoparticles are two different members selected from the group consisting of carbon nanotubes, cadmium telluride nanoparticles, graphene nanoparticles, magnetite nanoparticles, molybdenum disulfide nanoparticles, silver nanoparticles, palladium nanoparticles, gold nanoparticles, silicon nanoparticles, titanium oxide nanoparticles, and quantum dots.

### Claim 8 (depends on 1)

The method of claim 1, wherein the first nanoparticles are hematite nanoparticles and the second nanoparticles are carboxylated polystyrene nanoparticles.

### Claim 9 (depends on 1)

The method of claim 1, further comprising adjusting a concentration ratio of the second nanoparticles to the first nanoparticles to adjust a size of the core-shell nanohybrids.

### Claim 10 (depends on 1)

The method of claim 1, wherein a suspension of the core-shell nanohybrids is free of unaggregated first nanoparticles and unaggregated second nanoparticles without conducting a purification step.

### Claim 11 (depends on 10)

The method of claim 10, wherein a concentration ratio of the second nanoparticles to the first nanoparticles is minimized to form the suspension of the core-shell nanohybrids free of unaggregated first nanoparticles and unaggregated second nanoparticles.

### Claim 12 (depends on 1)

The method of claim 1, wherein the core comprises only one of the first nanoparticles.

### Claim 13 (depends on 1)

The method of claim 1, wherein the shell comprises nanogaps configured to allow access of substrates to the core.

### Claim 14

A nanohybrid comprising a core comprising at least one neutral nanoparticle within a shell comprising charged nanoparticles, wherein the shell further comprises nanogaps configured to allow access of substrates to the core.

### Claim 15 (depends on 14)

The nanohybrid of claim 14, wherein the shell comprises either positively charged nanoparticles or negatively charged nanoparticles.

### Claim 16 (depends on 14)

The nanohybrid of claim 14, wherein the at least one neutral nanoparticle and the charged nanoparticles are members selected from the group consisting of carbon nanotubes, cadmium telluride nanoparticles, graphene nanoparticles, magnetite nanoparticles, molybdenum disulfide nanoparticles, silver nanoparticles, palladium nanoparticles, gold nanoparticles, silicon nanoparticles, titanium oxide nanoparticles, and quantum dots.

### Claim 17 (depends on 14)

The nanohybrid of claim 14, wherein the at least one neutral nanoparticle comprises hematite nanoparticles and the charged nanoparticles comprise carboxylated polystyrene nanoparticles.