# US 2021/0276003 A1 · Fluid handling device

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- Number: US 2021/0276003 A1
- Document ID: US20210276003A1
- Status: Published application
- Kind: A1
- Application number: 17/181,122
- Filed: 2021-02-22
- Published: 2021-09-09
- Earliest claimed: 2020-03-04
- Assignees: Enplas Corporation
- Applicants: Enplas Corporation
- Inventors: Yasuhiro Watanabe; Seiichiro Suzuki
- Web page: https://patentgrep.com/patent/US20210276003A1

## CPC

- B01L 3/00: Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L 3/0241: {Drop counters; Drop formers}
- B01F 33/3011: using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
- B01L 3/502784: {specially adapted for droplet or plug flow, e.g. digital microfluidics}
- B81B 1/00: Devices without movable or flexible elements, e.g. microcapillary devices
- B01L 2200/0673: Handling of plugs of fluid surrounded by immiscible fluid
- B01L 2300/0887: Laminated structure
- B01L 2300/12: Specific details about materials
- B01L 2300/123: Flexible; Elastomeric
- B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01F: MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING (mixing paints B44D3/06)
- B81B: MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES (piezoelectric, electrostrictive or magnetostrictive elements per se H10N30/00, H10N35/00)

## Abstract

A fluid handling device of the present invention includes a substrate and a film adhered to one surface of the substrate. The substrate includes a sample channel groove; a dispersion medium channel groove; a dispersion liquid generation recess for forming a dispersion liquid generation part which is connected to the sample channel and the dispersion medium channel, and in which the sample is to be divided by the dispersion medium to generate a dispersion liquid, and a dispersion liquid channel groove for forming a dispersion liquid channel which is connected to the dispersion liquid generation part, and which is for allowing the dispersion liquid to flow. The film contains an adhesive coated with a coating material in parts facing the sample channel groove, the dispersion medium channel groove, the dispersion liquid generation recess, and the dispersion liquid channel groove.

## Claims

### Claim 1

A fluid handling device, comprising:
a substrate and a film adhered to one surface of the substrate, wherein the substrate includes
a sample channel groove for forming a sample channel along with the film, the sample channel being for allowing a sample to flow,
a dispersion medium channel groove for forming a dispersion medium channel along with the film, the dispersion medium channel being for allowing a dispersion medium to flow,
a dispersion liquid generation recess for forming a dispersion liquid generation part along with the film, the dispersion liquid generation part being connected to the sample channel and the dispersion medium channel, the dispersion liquid generation part being for generating a dispersion liquid containing a droplet of the sample dispersed in the dispersion medium by dividing the sample by the dispersion medium, and
a dispersion liquid channel groove for forming a dispersion liquid channel along with the film, the dispersion liquid channel being connected to the dispersion liquid generation part, the dispersion liquid channel being for allowing the dispersion liquid to flow, and wherein
the film contains an adhesive coated with a coating material in parts of the film, the parts facing the sample channel groove, the dispersion medium channel groove, the dispersion liquid generation recess, and the dispersion liquid channel groove.

### Claim 2 (depends on 1)

The fluid handling device according to claim 1, wherein the film is adhered to the one surface of the substrate by the adhesive.

### Claim 3 (depends on 1)

The fluid handling device according to claim 1, wherein the adhesive coated with the coating material is an encapsulated adhesive in a capsule.

### Claim 4 (depends on 1)

The fluid handling device according to claim 1, wherein the adhesive coated with the coating material is exposed by the coating material being destroyed by pressure.

### Claim 5 (depends on 1)

The fluid handling device according to claim 1, wherein the sample channel is for allowing a sample containing a solid to flow.