# US 2021/0275572 A1 · Methods for reducing cholesterol with superabsorbent materials > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0275572 A1 - Document ID: US20210275572A1 - Status: Published application - Kind: A1 - Application number: 17/327,037 - Filed: 2021-05-21 - Published: 2021-09-09 - Earliest claimed: 2018-08-10 - Assignees: Healthall Laboratory, Inc. - Applicants: Healthall Laboratory, Inc. - Inventors: Lijun SUN - Web page: https://patentgrep.com/patent/US20210275572A1 ## CPC - A61K 31/736: Glucomannans or galactomannans, e.g. locust bean gum, guar gum - A23L 33/30: {Dietetic or nutritional methods, e.g. for losing weight (A23L33/10 takes precedence)} - A61K 9/14: Particulate form, e.g. powders, {Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles (microspheres A61K9/16; microcapsules A61K9/50; nanocapsules, nanoparticles of the matrix type A61K9/51)} - A61K 31/718: Starch or degraded starch, e.g. amylose, amylopectin - A61K 31/722: Chitin, chitosan - A61K 31/723: Xanthans - A61K 31/729: Agar; Agarose; Agaropectin - A61K 31/731: Carrageenans - A61K 31/732: Pectin - A61K 31/734: Alginic acid - A61K 36/02: Algae - A61K 36/04: Rhodophycota or rhodophyta (red algae), e.g. Porphyra - A61K 36/888: Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage - A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca - A61P 3/04: Anorexiants; Antiobesity agents - A61P 3/06: Antihyperlipidemics - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract Methods for reducing cholesterol in a subject can include: providing a superabsorbent material that includes a porous network structure formed from a mixture of a plurality of water soluble polysaccharides that are not chemically crosslinked together; and administering the superabsorbent material to a subject in an effective amount to reduce cholesterol in the subject. The reduction of cholesterol includes at least one of: reducing total cholesterol of the subject; reducing a rate of total cholesterol increase in the subject; or increasing a rate of total cholesterol decrease in the subject. The reduction of cholesterol includes at least one of: reducing cholesterol intake into the subject; reducing cholesterol absorption by the gut of the subject; or absorbing cholesterol material from the gut of the subject into the superabsorbent material. The reduction of cholesterol is by reduction of low-density-lipoprotein cholesterol or high-density-lipoprotein cholesterol. ## Claims ### Claim 1 A method for reducing cholesterol in a subject, the method comprising: providing a superabsorbent material that includes a porous network structure formed from a mixture of a plurality of water soluble polysaccharides that are not chemically crosslinked together; and administering the superabsorbent material to a subject in an effective amount to reduce cholesterol in the subject. ### Claim 2 (depends on 1) The method of claim 1, wherein the reduction of cholesterol includes at least one of: reducing total cholesterol of the subject; reducing a rate of total cholesterol increase in the subject; or increasing a rate of total cholesterol decrease in the subject. ### Claim 3 (depends on 1) The method of claim 1, wherein the reduction of cholesterol includes at least one of: reducing cholesterol intake into the subject; reducing cholesterol absorption by the gut of the subject; or absorbing cholesterol material from the gut of the subject into the superabsorbent material. ### Claim 4 (depends on 1) The method of claim 1, wherein the reduction of cholesterol is by reduction of low-density-lipoprotein cholesterol. ### Claim 5 (depends on 1) The method of claim 1, wherein the reduction of cholesterol is by reduction of high-density-lipoprotein cholesterol. ### Claim 6 (depends on 1) The method of claim 1, comprising administering the superabsorbent material so that the subject has a slower rate of cholesterol gain, wherein the slower rate is compared to the subject having a higher rate of cholesterol gain prior to being administered the superabsorbent material. ### Claim 7 (depends on 1) The method of claim 1, wherein the subject has a high fat diet prior to being administered the superabsorbent material. ### Claim 8 (depends on 1) The method of claim 1, wherein the plurality of water soluble polysaccharides includes at least two of agar, konjac gum, carrageenan, locust bean gum, xanthan gum, tamarind seed gum, guar gum carrageenan, alginate, pectin, gellan gum, chitosan, Arabic gum, and a soluble starch. ### Claim 9 A method for reducing circulating lipid in a subject, the method comprising: providing a superabsorbent material that includes a porous network structure formed from a mixture of a plurality of water soluble polysaccharides that are not chemically crosslinked together; and administering the superabsorbent material to a subject in an effective amount to reduce circulating lipid in the subject. ### Claim 10 (depends on 9) The method of claim 9, wherein the reduction of circulating lipid includes at least one of: reducing amount of circulating lipid of the subject; reducing rate of circulating lipid increase in the subject; or increasing rate of circulating lipid decrease in the subject. ### Claim 11 (depends on 9) The method of claim 9, wherein the reduction of circulating lipid is reduction of low-density-lipoprotein. ### Claim 12 (depends on 9) The method of claim 9, wherein the reduction of circulating lipid is reduction of high-density-lipoprotein. ### Claim 13 (depends on 9) The method of claim 9, comprising administering the superabsorbent material so that the subject has a slower rate of circulating lipid gain, wherein the slower rate is compared to the subject having a higher rate of circulating lipid gain prior to being administered the superabsorbent material. ### Claim 14 (depends on 9) The method of claim 9, wherein the subject has a high fat diet prior to being administered the superabsorbent material. ### Claim 15 (depends on 9) The method of claim 9, wherein the plurality of water soluble polysaccharides includes at least two of agar, konjac gum, carrageenan, locust bean gum, xanthan gum, tamarind seed gum, guar gum carrageenan, alginate, pectin, gellan gum, chitosan, Arabic gum, and a soluble starch. ### Claim 16 (depends on 10) The method of claim 10, wherein the reduction of circulating lipid includes a reduction of circulating lipoprotein by at least one of: reducing amount of circulating lipoprotein of the subject; reducing rate of circulating lipoprotein increase in the subject; or increasing rate of circulating lipoprotein decrease in the subject. ### Claim 17 (depends on 16) The method of claim 16, wherein the lipoprotein is low-density-lipoprotein cholesterol. ### Claim 18 (depends on 16) The method of claim 16, wherein lipoprotein is high-density-lipoprotein cholesterol. ### Claim 19 (depends on 16) The method of claim 16, comprising administering the superabsorbent material so that the subject has a slower rate of circulating lipoprotein gain, wherein the slower rate is compared to the subject having a higher rate of circulating lipoprotein gain prior to being administered the superabsorbent material, wherein the lipoprotein is low-density-lipoprotein cholesterol or high-density-lipoprotein cholesterol. ### Claim 20 A kit for reducing cholesterol in a subject, the method comprising: a superabsorbent material that includes a porous network structure formed from a mixture of a plurality of water soluble polysaccharides that are not chemically crosslinked together; and instructions for a subject to consume the superabsorbent material in an effective amount to reduce cholesterol in the subject, wherein the cholesterol is low-density-lipoprotein cholesterol or high-density-lipoprotein cholesterol.