# US 2021/0275434 A1 · Virus inactivating agent

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2021/0275434 A1
- Document ID: US20210275434A1
- Status: Published application
- Kind: A1
- Application number: 17/261,263
- Filed: 2019-07-19
- Published: 2021-09-09
- Earliest claimed: 2018-07-20
- Assignees: Shiseido Company, Ltd.
- Applicants: Shiseido Company, Ltd.
- Inventors: Shoko ARINO; Hirohito SHIRAKAMI; Yukiko HIRUMA
- Web page: https://patentgrep.com/patent/US20210275434A1

## CPC

- A61K 8/922: {of vegetable origin}
- A61Q 17/005: {Antimicrobial preparations}
- A01N 65/00: Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof (containing compounds of determined constitution A01N27/00 - A01N59/00)
- A61K 8/06: Emulsions
- A61K 8/19: containing inorganic ingredients
- A61K 8/31: Hydrocarbons
- A61K 8/34: Alcohols
- A61K 8/362: Polycarboxylic acids
- A61K 8/416: {Quaternary ammonium compounds (A61K8/35 takes precedence)}
- A61K 8/731: {Cellulose; Quaternized cellulose derivatives}
- A61K 8/732: {Starch; Amylose; Amylopectin; Derivatives thereof}
- A61K 8/8152: {Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers}
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 31/718: Starch or degraded starch, e.g. amylose, amylopectin
- A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K 36/534: Mentha (mint)
- A61K 36/537: Salvia (sage)
- A61K 36/54: Lauraceae (Laurel family), e.g. cinnamon or sassafras
- A61P 17/00: Drugs for dermatological disorders
- A61P 31/12: Antivirals
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The purpose of the present invention is to provide: a virus inactivating agent that exhibits an effect at an amount that does not cause skin irritation; and an external skin preparation composition containing said virus inactivating agent. The present invention relates to: a virus inactivating agent containing, as an effective component thereof, at least one selected from mint oil, eucalyptus oil, rosemary oil, sage oil, tea tree oil, shell ginger oil, peppermint oil, lemongrass oil, cajeputi oil, niaouli cineole oil, lime oil, lemon oil, lemon verbena oil, St. John's wort oil, ravintsara oil, rosewood oil, Melissa/lemon balm oil, myrrh oil, mandarin oil, vetiver oil, frankincense oil, citronella oil, cardamom oil, Angelica oil, and cationized starch; and an external skin preparation composition containing the same.

## Claims

### Claim 1

A virus inactivating agent comprising, as active ingredient, one or two or more selected from the group consisting of mint oil, eucalyptus oil, rosemary oil, sage oil, tea tree oil, getto oil, peppermint oil, lemongrass oil, cajeput oil, niaouli cineole oil, lime oil, lemon oil, lemon verbena oil, St. John's wort oil, ravintsara oil, rosewood oil, melissa/lemon balm oil, myrrh oil, mandarin oil, vetiver oil, frankincense oil, citronella oil, cardamon oil, angelica oil, and cationic starch.

### Claim 2 (depends on 1)

The virus inactivating agent according to claim 1, comprising, as active ingredient, one or two or more selected from the group consisting of mint oil, eucalyptus oil, rosemary oil, and sage oil.

### Claim 3 (depends on 2)

The virus inactivating agent according to claim 2, comprising, as active ingredient, any three selected from the group consisting of mint oil, eucalyptus oil, rosemary oil, and sage oil.

### Claim 4 (depends on 2)

The virus inactivating agent according to claim 2, comprising, as active ingredient, mint oil, eucalyptus oil, rosemary oil, and sage oil.

### Claim 5 (depends on 1)

The virus inactivating agent according to claim 1, wherein a total content of limonene is 0.006% by mass or more.

### Claim 6 (depends on 1)

The virus inactivating agent according to claim 1, comprising the cationic starch as an active ingredient.

### Claim 7 (depends on 1)

The virus inactivating agent according to claim 1, wherein the cationic starch is a cationic polymer represented by the following formula (I):
wherein X— represents an anion derived from an inorganic acid or an organic acid; a is 0.6 to 0.9 and b is 0.4 to 0.1, provided that a and b satisfy a+b=1; and an average molecular weight is 30,000 to 1,000,000.

### Claim 8 (depends on 1)

The virus inactivating agent according to claim 1, wherein an average molecular weight of the cationic starch is 100,000 to 500,000.

### Claim 9 (depends on 1)

The virus inactivating agent according to claim 1, wherein the cationic starch is starch hydroxypropyltrimonium chloride.

### Claim 10 (depends on 1)

The virus inactivating agent according to claim 1, wherein a content of the cationic starch is 0.1% by mass or more.

### Claim 11 (depends on 1)

The virus inactivating agent according to claim 1, wherein the virus is an enveloped single-stranded RNA virus.

### Claim 12 (depends on 11)

The virus inactivating agent according to claim 11, wherein the enveloped single-stranded RNA virus is a virus belonging to family Orthomyxoviridae.

### Claim 13 (depends on 12)

The virus inactivating agent according to claim 12, wherein the virus belonging to family Orthomyxoviridae is influenza virus.

### Claim 14 (depends on 1)

A skin external-preparation composition comprising the virus inactivating agent according to claim 1.

### Claim 15 (depends on 14)

The skin external-preparation composition according to claim 14, further comprising an alcohol.

### Claim 16 (depends on 15)

The skin external-preparation composition according to claim 15, wherein a content of the alcohol is 50% by mass or less.