# US 2021/0275418 A1 · Personal Care Compositions > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0275418 A1 - Document ID: US20210275418A1 - Status: Published application - Kind: A1 - Application number: 17/195,715 - Filed: 2021-03-09 - Published: 2021-09-09 - Earliest claimed: 2020-03-09 - Assignees: Colgate-Palmolive Company - Applicants: Colgate-Palmolive Company - Inventors: Vinay BHARDWAJ; Aixing FAN; Jason NESTA; Thomas BOYD; Min LI - Web page: https://patentgrep.com/patent/US20210275418A1 ## CPC - A61K 8/365: Hydroxycarboxylic acids; Ketocarboxylic acids - A61Q 5/00: Preparations for care of the hair - A61K 8/36: Carboxylic acids; Salts or anhydrides thereof - A61Q 5/02: Preparations for cleaning the hair - A61Q 15/00: Anti-perspirants or body deodorants (deodorisation of air A61L9/00) - A61Q 19/00: Preparations for care of the skin - A61Q 19/007: {Preparations for dry skin} - A61Q 19/10: Washing or bathing preparations - A61K 2800/28: Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants - A61K 2800/5922: At least two compounds being classified in the same subclass of A61K8/18 - A61K 2800/74: Biological properties of particular ingredients - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Described herein are personal care compositions comprising a complex comprising a plurality of short chain fatty acids; along with methods of making and using same. ## Claims ### Claim at position 1 1-45. (canceled) ### Claim 46 A personal care composition comprising: a complex comprising a plurality of short chain fatty acids; and a cosmetically acceptable carrier. ### Claim 47 (depends on 46) The personal care composition according to claim 46, wherein the plurality of short chain fatty acids comprises: a first component comprising a first short chain fatty acid, a derivative thereof or a salt thereof; a second component comprising a second short chain fatty acid, a derivative thereof; or a salt thereof; and a third component comprising a third short chain fatty acid, a derivative thereof; or a salt thereof. ### Claim 48 (depends on 46) The personal care composition according to claim 46, wherein the plurality of short chain fatty acids comprises at least one short chain fatty acid selected from: lactic acid; pyruvic acid; mandelic acid; butanedioic acid (e.g. succinic acid); formic acid; propionic acid; butyric acid; isobutyric acid; valeric acid; isovaleric acid; a derivative thereof; a salt thereof (e.g. sodium pyruvate); and a combination of two or more thereof. ### Claim 49 (depends on 47) The personal care composition according to claim 47, wherein the first short chain fatty acid is present in an amount greater than the second short chain fatty acid. ### Claim 50 (depends on 49) The personal care composition according to claim 49, wherein the second short chain fatty acid is present in an amount greater than the third short chain fatty acid. ### Claim 51 (depends on 47) The personal care composition according to claim 47, wherein the weight ratio of the first short chain fatty acid to the second short chain fatty acid is from about 4:1 to about 1:4. ### Claim 52 (depends on 51) The personal care composition according to claim 51, wherein the weight ratio of the first short chain fatty to the third short chain fatty acid is from about 8:1 to about 1:8. ### Claim 53 (depends on 52) The personal care composition according to claim 52, wherein the weight ratio of the second short chain fatty acid to the third short chain fatty acid is from about 4:1 to about 1:4. ### Claim 54 (depends on 47) The personal care composition according to claim 47, wherein the first short chain fatty acid comprises lactic acid, or a salt thereof. ### Claim 55 (depends on 47) The personal care composition according to claim 47, wherein the second short chain fatty acid comprises mandelic acid, or a salt thereof. ### Claim 56 (depends on 47) The personal care composition according to claim 47, wherein the third short chain fatty acid comprises pyruvic acid, or a salt thereof. ### Claim 57 (depends on 46) The personal care composition according to claim 46, wherein the complex comprising a plurality of short chain fatty acids is present in an anti-microbial effective amount. ### Claim 58 (depends on 46) The personal care composition according claim 46, wherein the composition is in a form selected from a body wash; a hand soap; a shower gel; a wipe; a lotion; a cream; an ointment; an antiperspirant; a peel (e.g., a chemical peel); and a deodorant. ### Claim 59 (depends on 46) The personal care composition according to claim 46, comprising: from about 2 to about 20 wt. % lactic acid, or a salt thereof; from about 1 to about 12 wt. % mandelic acid, or a salt thereof; and from about 0.5 to about 8 wt. % pyruvic acid, or a salt thereof. ### Claim 60 (depends on 46) The personal care composition according to claim 46, comprising: from about 4 to about 18 wt. % lactic acid, or a salt thereof; from about 2 to about 10 wt. % mandelic acid, or a salt thereof; and from about 0.5 to about 6 wt. % pyruvic acid, or a salt thereof. ### Claim 61 (depends on 60) The personal care composition according to claim 60, comprising lactic acid, or a salt thereof, mandelic acid, or a salt thereof; and pyruvic acid, or a salt thereof, in a weight ratio of about 4:2:1. ### Claim 62 (depends on 60) The personal care composition according to claim 60, wherein the salt of pyruvic acid is sodium pyruvate. ### Claim 63 A method of treating, preventing or ameliorating a symptom associated with a disease, disorder or condition of the skin, comprising administering to the skin of a subject in need thereof, an effective amount of a personal care composition comprising a complex comprising a plurality of short chain fatty acids; and a cosmetically acceptable carrier; wherein the plurality of short chain fatty acids comprises at least one short chain fatty acid selected from: lactic acid; pyruvic acid; mandelic acid; butanedioic acid (e.g. succinic acid); formic acid; propionic acid; butyric acid; isobutyric acid; valeric acid; isovaleric acid; a derivative thereof a salt thereof (e.g. sodium pyruvate); and a combination of two or more thereof. ### Claim 64 (depends on 63) The method according to claim 63, wherein the effective amount is an amount capable of promoting the growth of beneficial bacteria and/or inhibiting the growth of harmful bacteria. ### Claim 65 A method for inhibiting: tyrosinase; collagenase; and/or elastase; in a patient in need thereof, comprising administering to the skin of said patient, an effective amount of a personal care composition comprising a complex comprising a plurality of short chain fatty acids; and a cosmetically acceptable carrier; wherein the plurality of short chain fatty acids comprises: a first component comprising a first short chain fatty acid, a derivative thereof or a salt thereof; a second component comprising a second short chain fatty acid, a derivative thereof or a salt thereof; and a third component comprising a third short chain fatty acid, a derivative thereof or a salt thereof.