# US 2021/0275334 A1 · System & methods for compressing endovascular devices > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2021/0275334 A1 - Document ID: US20210275334A1 - Status: Published application - Kind: A1 - Application number: 16/810,481 - Filed: 2020-03-05 - Published: 2021-09-09 - Earliest claimed: 2020-03-05 - Assignees: Fluid Biotech Inc. - Applicants: fluid biotech inc. - Inventors: Alim P. MITHA; MEHDI JAMSHIDI - Web page: https://patentgrep.com/patent/US20210275334A1 ## CPC - A61F 2/9525: {using a funnel} - A61F 2/966: with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod - A61F 2/958: Inflatable balloons for placing stents or stent-grafts - A61F 2002/9511: {the retaining means being filaments or wires} - A61F 2002/9665: {with additional retaining means} - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract This disclosure relates to systems and methods for compressing reversibly compressible endovascular devices for loading into delivery catheters prior to deployment in lumen of a vessel. ## Claims ### Claim 1 A system for the radial compression of a reversibly compressible endovascular device (ED) prior to deployment, the system comprising: the ED, wherein the ED comprises a tubular body, wherein the body is expandable between a compressed position and an non-compressed position, the tubular body having an inner surface, an outer surface, opposed distal and proximal ED ends, and opposed distal and proximal ED openings; a delivery sheath sized to receive and maintain the ED in the compressed position, the delivery sheath having a delivery sheath opening having a diameter sized to receive the ED into the delivery sheath in a compressed form; a collapsible compressor for compressing the ED for reception by the delivery sheath through the delivery sheath opening, wherein the compressor comprises: a generally tapered structure defining an interior space, the tapered structure comprising distal and proximal compressor ends, wherein the proximal compressor end is proximal to the delivery sheath opening, wherein the distal compressor end comprises a distal compressor opening sized to receive the ED in the non-compressed position, wherein the tapered structure tapers from the distal compressor opening toward the proximal compressor end such that the cross section of the interior space diminishes toward the proximal compressor end, wherein the cross sectional area of the interior space at the proximal compressor end is equal to or less than the cross sectional area of the delivery sheath opening, and wherein an interior surface of the tapered structure is frictionally engaged with the outer surface of the ED; and a hollow compressor tube attached to the compressor and disposed within the delivery sheath, wherein the hollow compressor tube is operable to be advanced proximally through the delivery sheath to urge the compressor and the ED frictionally engaged therein through the delivery sheath opening to collapse the compressor, wherein collapse of the compressor upon reception within the delivery sheath exerts a radial force upon the ED sufficient to compress the ED into the compressed position for reception in the delivery sheath; and a push wire disposed within the hollow compressor tube and operable to be advanced through the delivery sheath independently of the hollow compressor tube, wherein the push wire has a bump member disposed thereon proximal to the proximal ED end, and wherein the bump member is configured to abut the ED on the proximal ED end. ### Claim 2 (depends on 1) The system of claim 1, wherein the compressor comprises a proximal compressor opening at the proximal compressor end, wherein the proximal compressor opening is in communication with the hollow compressor tube. ### Claim 3 (depends on 2) The system of claim 2, wherein the width of the proximal compressor opening is smaller than the radial diameter of the ED when the ED is in the non-compressed position. ### Claim 4 (depends on 2) The system of claim 2, wherein the push wire is disposed within the ED through the proximal compressor opening, and wherein the push wire is operable to be advanced proximally through the delivery sheath. ### Claim 5 (depends on 1) The system of claim 1, wherein the compressor is at least one of a funnel or is reversibly collapsible. ### Claim 6 (canceled) ### Claim 7 (canceled) ### Claim 8 (canceled) ### Claim 9 (canceled) ### Claim 10 (canceled) ### Claim 11 (depends on 1) The system of claim 1, wherein the compressor comprises a braided structure. ### Claim 12 (depends on 11) The system of claim 11, wherein the braided structure is a polypropylene braided structure or a metal braided structure. ### Claim 13 (depends on 1) The system of claim 1, wherein the tapered structure comprises a plurality of overlapping tongues coupled at the proximal compressor end, wherein each tongue tapers toward the proximal compressor end. ### Claim 14 (depends on 1) The system of claim 1, wherein the proximal compressor end is sized to be received within the delivery sheath through the delivery sheath opening. ### Claim 15 (depends on 14) The system of claim 14, wherein the compressor is sized to be received within the delivery sheath when the compressor is in a collapsed position. ### Claim 16 (canceled) ### Claim 17 (canceled) ### Claim 18 (canceled) ### Claim 19 (canceled) ### Claim 20 (canceled) ### Claim 21 (canceled) ### Claim 22 (canceled) ### Claim 23 (canceled) ### Claim 24 (depends on 1) The system of claim 1, wherein the ED is a self-expanding ED. ### Claim 25 (depends on 1) A system for deploying a reversibly compressible endovascular device within a lumen of a vessel, the system comprising: a system for the radial compression of a reversibly compressible endovascular device (ED) prior to deployment as defined in claim 1; a delivery catheter comprising proximal and distal delivery catheter openings, wherein the distal delivery catheter opening is for deploying the ED in to the lumen, and wherein the proximal delivery catheter opening is for receiving the ED from the delivery sheath, wherein the proximal delivery catheter opening is of a width equal to or greater than the width of the delivery sheath opening; and a hub connected to the proximal delivery catheter opening, the hub having a hub opening for receiving the delivery sheath in the hub when the ED is positioned in the delivery sheath, and positioning the delivery sheath in abutment with the proximal delivery catheter opening, wherein the push wire is operable to be advanced through the delivery catheter to urge the ED through the delivery catheter and out distal delivery catheter opening. ### Claim 26 A method of loading a reversibly compressible endovascular device (ED) into a delivery sheath having an interior width less than the radial width of the ED in an unexpanded position, the method comprising: compressing the ED from an expanded position to an unexpanded position for reception in the delivery sheath, wherein compressing comprises urging the ED in the expanded position through an interior space of a compressor, wherein the compressor comprises a tapered structure tapered from a distal compressor end toward a proximal compressor end of the tapered structure, wherein the width of the interior space at the distal compressor end is greater than the diameter of the ED in the expanded position and the width of the interior space at the proximal compressor end is less than the diameter of the ED in the expanded position, to radially compress the ED to an unexpanded position; urging the ED in the unexpanded position through a proximal compressor opening at the proximal compressor end and into the delivery sheath through a delivery sheath opening. ### Claim 27 (depends on 26) The method of claim 26, wherein the tapered structure is resiliently collapsible. ### Claim 28 (depends on 27) The method of claim 27, wherein the tapered structure comprises a plurality of overlapping tongues coupled at the proximal compressor end, wherein each tongue tapers toward the proximal compressor end. ### Claim 29 (depends on 28) The method of claim 28, wherein each tongue is slidable over an adjacent tongue to change the cross sectional area of the interior space. ### Claim 30 A system for the radial compression of a reversibly compressible endovascular device (ED) prior to deployment, the system comprising: the ED, wherein the ED comprises a tubular body, wherein the body is self-expandable between a compressed position and a non-compressed position, the tubular body having an inner surface, an outer surface, opposed distal and proximal ED ends, and opposed distal and proximal ED openings; a delivery catheter sized to receive and maintain the ED in the compressed position, the delivery catheter having proximal and distal delivery catheter ends, and a distal delivery catheter opening at the distal delivery catheter end, wherein the distal delivery catheter opening has a diameter sized to receive the ED into the delivery catheter in a compressed form; a collapsible compressor for compressing the ED for reception by the delivery catheter through the distal delivery catheter opening, wherein the compressor comprises: a generally tapered structure defining an interior space, the tapered structure comprising distal and proximal compressor ends, wherein the proximal compressor end is proximal to the distal delivery catheter opening, wherein the distal compressor end comprises a distal compressor opening sized to receive the ED in the non-compressed position, wherein the tapered structure tapers from the distal compressor end toward the proximal compressor end such that the cross section of the interior space diminishes toward the proximal compressor end, wherein the cross sectional area of the interior space at the proximal compressor end is equal to or less than the cross sectional area of the distal delivery catheter opening, and wherein an interior surface of the tapered structure is frictionally engaged with the outer surface of the ED; and a hollow compressor tube attached to the compressor and disposed within the delivery catheter, wherein the hollow compressor tube is operable to be advanced proximally through the delivery catheter toward the proximal delivery catheter end to urge the compressor and the ED frictionally engaged therein through the distal delivery catheter opening, wherein collapse of the compressor upon reception within the delivery catheter exerts a radial force upon the ED sufficient to compress the ED into the compressed position for reception in the delivery catheter; and a push wire disposed within the hollow compressor tube and operable to be advanced through the delivery catheter independently of the hollow compressor tube, wherein the push wire has a bump member disposed thereon proximal to the proximal ED end, wherein the bump member is configured to abut the ED on the proximal ED end. ### Claim 31 (depends on 30) The system of claim 30, wherein the compressor comprises a proximal compressor opening at the proximal compressor end, wherein the proximal compressor opening is in communication with the hollow compressor tube. ### Claim 32 (depends on 31) The system of claim 31, wherein the width of the proximal compressor opening is smaller than the radial diameter of the ED when the ED is in the non-compressed position. ### Claim 33 (depends on 31) The system of claim 31, wherein the push wire is disposed within the ED through the proximal compressor opening, and wherein the push wire is operable to be advanced proximally through the delivery catheter. ### Claim 34 (depends on 30) The system of claim 30, wherein the compressor is a funnel, comprises a braided structure, or is reversibly collapsible. ### Claim 35 (depends on 30) The system of claim 30, wherein the compressor comprises a polypropylene braided structure or a metal braided structure. ### Claim 36 (depends on 30) The system of claim 30, wherein the tapered structure comprises a plurality of overlapping tongues coupled at the proximal compressor end, and wherein each tongue tapers toward the second compressor end. ### Claim 37 (depends on 30) The system of claim 30, wherein the proximal compressor end is sized to be received within the delivery catheter through the distal delivery catheter opening. ### Claim 38 (depends on 37) The system of claim 37, wherein the compressor is sized to be received within the delivery catheter when the compressor is in a collapsed position. ### Claim 39 (depends on 30) The system of claim 30, wherein the ED is a self-expanding ED. ### Claim 40 (depends on 30) The system of claim 30, wherein the bump member is configured to abut the ED on the proximal ED end to apply a force to the ED to disengage the ED from the compressor. ### Claim 41 (depends on 40) The system of claim 40, wherein the bump member is configured to apply a force to the ED uniformly on the circumference of the proximal ED opening. ### Claim 42 (depends on 1) The system of claim 1, wherein the bump member is configured to abut the ED on the proximal ED end to apply a force to the ED to disengage the ED from the compressor. ### Claim 43 (depends on 42) The system of claim 42, wherein the bump member is configured to apply the force to the ED uniformly on the circumference of the proximal ED opening.