# US 2021/0275069 A1 · Instrument delivery devices, systems, and methods to extend through a thrombus

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- Number: US 2021/0275069 A1
- Document ID: US20210275069A1
- Status: Published application
- Kind: A1
- Application number: 17/183,098
- Filed: 2021-02-23
- Published: 2021-09-09
- Earliest claimed: 2020-03-09
- Assignees: Becton, Dickinson and Company
- Applicants: Becton, Dickinson and Company
- Inventors: Yiping Ma; Jordan Ciciliano; Jonathan Karl Burkholz
- Web page: https://patentgrep.com/patent/US20210275069A1

## CPC

- A61B 5/15003: {for venous or arterial blood}
- A61B 5/150992: {Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; Blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings or valves}
- A61B 5/150343: {Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes (sampling from within body cavities A61B5/150015, A61B5/150045)}
- A61B 5/154: {Devices} using pre-evacuated means
- A61B 5/155: {Devices} specially adapted for continuous or multiple sampling, e.g. at predetermined intervals {(devices loaded with multiple lancets simultaneously A61B5/15146)}
- A61M 25/007: {Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked}
- A61M 25/0606: {"Over-the-needle" catheter assemblies, e.g. I.V. catheters}
- A61M 25/0113: {Mechanical advancing means, e.g. catheter dispensers}
- A61M 25/0693: {Flashback chambers}
- A61M 2025/0008: {having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A method may include coupling a first delivery device to a catheter assembly, which may include a catheter dwelling within vasculature of a patient. The first delivery device may include a first tubular instrument. In response to the first tubular instrument being in a distal position, a distal surface of the first tubular instrument may be disposed at a first distance beyond the distal tip of the catheter. The method may include coupling a second delivery device to the catheter assembly after uncoupling the first delivery device from the catheter assembly. The second delivery device may include a second tubular instrument. In response to the second tubular instrument being in the distal position, a distal surface of the second tubular instrument may be disposed at a second distance beyond the distal tip of the catheter. The second distance may be greater than the first distance.

## Claims

### Claim 1

A method, comprising:
coupling a first delivery device to a catheter assembly, wherein the catheter assembly comprises a catheter dwelling within vasculature of a patient, wherein the first delivery device comprises:
a first housing; and
a first tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the first tubular instrument and the proximal end of the first tubular instrument, wherein the proximal end of the first tubular instrument is secured within the first housing, wherein the first tubular instrument is configured to advance distally from a proximal position to a distal position with respect to the first housing and the catheter assembly, wherein in response to the first tubular instrument being in the proximal position, the first tubular instrument is proximal to the catheter assembly, wherein in response to the first tubular instrument being in the distal position, a distal surface of the first tubular instrument is disposed distal to a distal tip of the catheter and at a first distance beyond the distal tip of the catheter;
after transferring a first volume of blood via the first tubular instrument to a first blood collection container and moving the tubular instrument from the distal position toward the proximal position, decoupling the first delivery device from the catheter assembly;
after decoupling the first delivery device from the catheter assembly, coupling a second delivery device to the catheter assembly, wherein the second delivery device comprises:
a second housing;
a second tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the second tubular instrument and the proximal end of the second tubular instrument, wherein the proximal end of the second tubular instrument is secured within the second housing, wherein the second tubular instrument is configured to advance distally from another proximal position to another distal position with respect to the second housing and the catheter, wherein in response to the second tubular instrument being in the proximal position, the second tubular instrument is proximal to the catheter assembly, wherein in response to the second tubular instrument being in the distal position, a distal surface of the second tubular instrument is disposed distal to the distal tip of the catheter and at a second distance from the distal tip of the catheter, wherein the second distance is greater than the first distance; and
after transferring a second volume of blood via the second tubular instrument to a second blood collection container and moving the second tubular instrument from the distal position toward the proximal position, decoupling the second delivery device from the catheter.

### Claim 2 (depends on 1)

The method of claim 1, wherein a difference between the first distance and the second distance is 0.5 inches.

### Claim 3 (depends on 1)

The method of claim 1, wherein the first distance is 1 inch or less.

### Claim 4 (depends on 3)

The method of claim 3, wherein the second distance is 1.5 inches or less.

### Claim 5 (depends on 1)

The method of claim 1, further comprising transferring the first volume of blood via the first tubular instrument to the first blood collection container on a first day, further comprising transferring the second volume of blood via the second tubular instrument to the second blood collection container on a second day.

### Claim 6 (depends on 1)

The method of claim 1, wherein the distal end of the first tubular instrument and the second tubular instrument are closed.

### Claim 7 (depends on 1)

The method of claim 1, wherein the distal end of the first tubular instrument and the distal end of the second tubular instrument comprise a plurality of side holes.

### Claim 8 (depends on 1)

The method of claim 1, further comprising:
coupling a third delivery device to a catheter disposed within the vasculature of the patient, wherein the third delivery device comprises:
a third housing;
a third tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the third tubular instrument and the proximal end of the third tubular instrument, wherein the proximal end of the third tubular instrument is secured within the third housing, wherein the third tubular instrument is configured to advance distally from another proximal position to another distal position with respect to the third housing and the catheter, wherein in response to the third tubular instrument being in the other proximal position, the third tubular instrument is proximal to the catheter assembly, wherein in response to the third tubular instrument being in the other distal position, a distal surface of the third tubular instrument is disposed distal to the distal tip of the catheter and at a third distance from the distal tip of the catheter, wherein the third distance is greater than the second distance.

### Claim 9 (depends on 8)

The method of claim 8, wherein the third distance is 2.0 inches or less.

### Claim 10 (depends on 9)

The method of claim 9, wherein a difference between the second distance and the third distance is 0.5 inches.

### Claim 11

A blood draw kit, comprising:
a first delivery device, comprising:
a first housing, wherein a distal end of the first housing comprises a first adapter configured to couple to a catheter assembly; and
a first tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the first tubular instrument and the proximal end of the first tubular instrument, wherein the proximal end of the first tubular instrument is secured within the first housing, wherein the first tubular instrument is configured to advance distally from a proximal position to a distal position with respect to the first housing and the catheter assembly, wherein in response to the first tubular instrument advancing distally from the proximal position to the distal position with respect to the first housing, a distal surface of the distal end of the first tubular instrument is disposed at a first distance beyond the distal end of the first housing;
a second delivery device, comprising:
a second housing, wherein a distal end of the second housing comprises a second adapter configured to couple to a catheter assembly; and
a second tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the second tubular instrument and the proximal end of the second tubular instrument, wherein the proximal end of the second tubular instrument is secured within the second housing, wherein the second tubular instrument is configured to advance distally from a proximal position to a distal position with respect to the second housing and the catheter assembly, wherein in response to the second tubular instrument advancing distally from the proximal position to the distal position with respect to the second housing, a distal surface of the distal end of the second tubular instrument is disposed at a second distance beyond the distal end of the second housing, wherein the second distance is greater than the first distance.

### Claim 12 (depends on 11)

The blood draw kit of claim 11, wherein the distal end of the first tubular instrument and the second tubular instrument are closed.

### Claim 13 (depends on 11)

The blood draw kit of claim 11, wherein the distal end of the first tubular instrument and the distal end of the second tubular instrument comprise a plurality of side holes.

### Claim 14 (depends on 11)

The blood draw kit of claim 11, further comprising:
a third delivery device, comprising:
a third housing, wherein a distal end of the third housing comprises a third adapter configured to couple to a catheter assembly; and
a third tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the third tubular instrument and the proximal end of the third tubular instrument, wherein the proximal end of the third tubular instrument is secured within the third housing, wherein the third tubular instrument is configured to advance distally from a proximal position to a distal position with respect to the third housing and the catheter assembly, wherein in response to the third tubular instrument advancing distally from the proximal position to the distal position with respect to the third housing, a distal surface of the distal end of the third tubular instrument is disposed at a third distance beyond the distal end of the third housing, wherein the third distance is greater than the second distance.

### Claim 15

A delivery device to deliver a tubular instrument through a catheter of a catheter assembly, the delivery device comprising:
a housing, comprising a first marking, a second marking, and a slot, wherein the first marking is proximal to the second marking;
a tubular instrument, comprising a distal end, a proximal end, and a lumen extending between the distal end of the tubular instrument and the proximal end of the tubular instrument, wherein the proximal end of the tubular instrument is secured within the housing,
a slider coupled to the tubular instrument and slidable along the slot of the housing, wherein in response to advancing the slider distally from a proximal position to the first marking, a distal surface of the distal end of the tubular instrument is disposed at a first distance beyond the distal end of the housing, wherein in response to advancing the slider distally from the proximal position to the second marking, the distal surface of the distal end of the tubular instrument is disposed at a second distance beyond the distal end of the housing, wherein second distance is greater than the first distance.

### Claim 16 (depends on 15)

The delivery device of claim 15, wherein a difference between the first distance and the second distance is 0.5 inches.

### Claim 17 (depends on 15)

The delivery device of claim 15, wherein the first distance is 1 inch or less.

### Claim 18 (depends on 17)

The delivery device of claim 17, wherein the second distance is 1.5 inches or less.

### Claim 19 (depends on 15)

The delivery device of claim 15, wherein the housing comprises a third marking distal to the second marking, wherein in response to advancing the slider distally from the proximal position to the third marking, the distal surface of the distal end of the tubular instrument is disposed at a third distance beyond the distal end of the housing, wherein third distance is greater than the second distance.

### Claim 20 (depends on 15)

The delivery device of claim 15, wherein in response to the slider being aligned with the first marking, the second marking, the third marking, or another marking on the housing, a distal surface of the tubular instrument is flush with a distal tip of the catheter.