# US 2021/0274814 A1 · Infusion of emulsified hydrophobic active ingredients into high polyphenolic beverages

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- Number: US 2021/0274814 A1
- Document ID: US20210274814A1
- Status: Published application
- Kind: A1
- Application number: 17/228,488
- Filed: 2021-05-17
- Published: 2021-09-09
- Earliest claimed: 2019-07-03
- Assignees: Vertosa Inc.
- Applicants: Vertosa, Inc.
- Inventors: CHUNXIAO HAN
- Web page: https://patentgrep.com/patent/US20210274814A1

## CPC

- A23L 2/52: Adding ingredients (adding preservatives A23B70/10)
- A23L 2/56: Flavouring or bittering agents (sweeteners A23L2/60)
- A23L 33/11: Plant sterols or derivatives thereof, e.g. phytosterols
- A23L 33/115: Fatty acids or derivatives thereof; Fats or oils
- A23L 35/10: {Emulsified foodstuffs}
- C12G 3/026: with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides, added before or during the fermentation stage; with flavouring ingredients added before or during the fermentation stage
- C12G 3/055: extracted from plants
- C12G 3/08: by methods for altering the composition of fermented solutions or alcoholic beverages not provided for in groups C12G3/02 - C12G3/07 (methods for reducing the alcohol content of fermented solutions or alcoholic beverages C12H3/00; methods for increasing the alcohol content of fermented solutions or alcoholic beverages C12H6/00)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- C12G: WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES (beer C12C); PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H

## Abstract

Disclosed herein are beverage compositions comprising a mixture of: (a) an emulsion of about 2 wt % of a cannabinoid; about 2-10 wt % of a carrier oil; about 2-24 wt % of an amphipathic glycoside; and about 64-94 wt % of water; and (b) a polyphenol or tannin rich beverage base, wherein the beverage composition does not precipitate over an extended time. Also disclosed herein are methods of making and using the same.

## Claims

### Claim 1

An emulsion system for producing a cannabis-infused beverage, comprising:
an emulsion comprising about 2-32 wt % cannabinoid; about 2-10 wt % of a carrier oil; about 2-24 wt % of an amphipathic glycoside composition; and about 64-94 wt % of water; and
wherein the emulsion is capable of being mixed with a high-polyphenolic beverage to produce a cannabis-infused beverage, wherein the transparency, taste, or experience of the cannabis-infused beverage is determined by the emulsion that is selected for use in the system.

### Claim 2 (depends on 49)

The emulsion system of claim 49, wherein the amphipathic glycoside composition comprises one or more of sucrose monoester of lauric acid, sucrose monoester of palmitic acid, sunflower lecithin, quillaja saponin, and gum acacia.

### Claim 3 (depends on 50)

The emulsion system of claim 50, comprising one or more sucrose esters and sunflower lecithin; wherein the carrier oil amount is at least the same amount as the cannabinoid, the sucrose esters are at least 0.5 times the total amount of cannabinoid and carrier oil, and the sunflower lecithin is at least 0.15 times the amount of sucrose esters.

### Claim 4 (depends on 49)

The emulsion system of claim 49, wherein the concentration of the cannabinoid in the beverage composition is between 10-500 mg/750 mL.

### Claim 5 (depends on 52)

The emulsion system of claim 52, wherein the emulsion comprises an average droplet size of 80-500 nm, wherein the turbidity is 22-1415 NTU, wherein the turbidity increases with average droplet size, and wherein the turbidity increases with cannabinoid concentration.

### Claim 6 (depends on 50)

The emulsion system of claim 50, wherein the amount of carrier oil is at least equal to the amount of the cannabinoid, wherein the amphipathic glycoside composition is quillaja saponin, wherein the quillaja saponin is at least 0.25 times the total amount of the cannabinoid and the carrier oil.

### Claim 7 (depends on 50)

The emulsion system of claim 50, wherein the carrier oil is at least the same amount as the cannabinoid, wherein the amphipathic glycoside composition is gum acacia, wherein the gum acacia is at least 1.5 times the total amount of cannabinoid and carrier oil.

### Claim 8 (depends on 49)

The emulsion system of claim 49, wherein the carrier oil comprises one or more of sunflower oil, olive oil, coconut oil, sesame oil, avocado oil, palm oil, soybean oil, corn oil, peanut oil, canola oil, or other type of medium-chain triglyceride oil.

### Claim 9 (depends on 49)

The emulsion system of claim 49, wherein the cannabinoid is selected from the group consisting of Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C (THCA-C), Tetrahydrocannbinol C (THC-C), Tetrahydrocannabi varinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C), Tetrahydrocannabiorcol (THC-C), Delta-7-cis-iso-tetrahydrocannabivarin, A-tetrahydrocannabinolic acid (A8-THCA), A-tetrahydrocannabinol (A-THC), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethyl ether (CBDM), Cannabidiol-C(CBD-C), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C), Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CB CVA), Cannabichromevarin (CBCV), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C(CBN-C), Cannabivarin (CBV), Cannabino-C(CBN-C), Cannabiorcol (CBN-C), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-A″-tetrahydrocannabinol, 8.9-Dihydroxy-A′-tetrahydrocannabinol (8.9-Di-OH CBT-C), Cannabitriolvarin (CBTV), Ethoxy-cannabitriol varin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-A′-tetrahydrocannabinol (OTHC), A-cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trim ethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triCH-THC), Isocanabinoids, and Epigallocatechin gallate.

### Claim 10 (depends on 49)

The emulsion system of claim 49, wherein the beverage is one or more of red wine, de-alcoholized red wine, rosé wine, de-alcoholized rosé wine, green tea, black tea, a fruit juice selected from pomegranate juice, grape juice, white grape juice, cranberry juice, raspberry juice, apple juice, watermelon juice, beetroot juice, orange juice, peach juice, grapefruit juice, cherry juice, blueberry juice, cranberry juice, black elderberry juice, blackcurrant juice, plum juice, blackberry juice, strawberry juice, apricot juice, young coconut water, or any combination thereof.

### Claim 11 (depends on 50)

The emulsion system of claim 50, wherein the quillaja saponin extract comprises Q-Naturale 100, Q-Naturale 200, Q-Naturale 200V, and/or Q-Naturale 300.

### Claim 12 (depends on 50)

The emulsion system of claim 50, wherein the gum acacia is unhydrolyzed gum acacia, pre-hydrolyzed gum acacia or TICALOID Acacia MAX.

### Claim 13 (depends on 49)

The emulsion system of claim 49, wherein the emulsion is compatible with a sterilization process, wherein the sterilization process is selected from one or more of tunnel pasteurization, retort, high temperature short time, aseptic, hot fill or dimethyldicarbonate.

### Claim 14 (depends on 49)

The emulsion system of claim 49, wherein the composition is capable of being stored for at least 3 years without aggregation or precipitation.

### Claim 15 (depends on 49)

The emulsion system of claim 49, wherein the emulsion further comprises one or more of vitamin A, vitamin D, vitamin E, vitamin K, DHA, omega 3, punicic acid (omega 5), fish oil, flaxseed oil, hemp seed oil, curcumin, lutein, CoQ-10, flavor oil or terpenes.

### Claim 16 (depends on 49)

The emulsion system of claim 49, wherein the cannabis-infused beverage is capable of being organically certified.

### Claim 17

A method of controlling onset and offset time of a cannabinoid in a high polyphenol beverage the method comprising infusing an emulsion of (a) about 2 wt % of a cannabinoid; (b) about 2-10 wt % of a carrier oil; (c) about 2-24 wt % of an amphipathic glycoside composition; and (d) about 64-94 wt % of water into a high-polyphenol beverage:
providing a sucrose ester and sunflower lecithin as the amphipathic glycoside composition for an onset time of 5-10 minutes and an offset time of about 3 hours; or
providing an extract of a quillaja saponin as the amphipathic glycoside composition for an onset time of about 10 minutes and an offset time of about 5 hours; or
providing gum acacia and/or pre-hydrolyzed gum acacia as the amphipathic glycoside composition for an onset time of about 20 minutes and an offset time of about 6 hours.

### Claim 18

A method of controlling the taste of a cannabis-infused high-polyphenol beverage, the method comprising, infusing an emulsion of (a) about 2 wt % of a cannabinoid; (b) about 2-10 wt % of a carrier oil; (c) about 2-24 wt % of an amphipathic glycoside composition; and (d) about 64-94 wt % of water into a high-polyphenol beverage; and
providing a sucrose ester and sunflower lecithin as the amphipathic glycoside solution to provide an increased bitter taste compared to the beverage without the emulsion; or
providing an extract of a quillaja saponin as the amphipathic glycoside composition to provide the same level of bitter taste compared to the beverage without the emulsion; or
providing gum acacia and/or pre-hydrolyzed gum acacia as the amphipathic glycoside composition to provide a decreased bitter taste compared to the beverage without the emulsion.