# US 2021/0274785 A1 · Synergistic Fungicidal Mixtures and Compositions Comprising 5-Fluoro-4-Imino-3-Methyl-1-Tosyl-3,4-Dihydropyrimidin-2(1h)-One for Fungal Control (SBI)

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2021/0274785 A1
- Document ID: US20210274785A1
- Status: Published application
- Kind: A1
- Application number: 17/329,837
- Filed: 2021-05-25
- Published: 2021-09-09
- Earliest claimed: 2013-12-31
- Assignees: Adama Makhteshim Ltd.
- Applicants: Adama Makhteshim Ltd.
- Inventors: W. John Owen; Chenglin Yao; Beth Lorsbach
- Web page: https://patentgrep.com/patent/US20210274785A1

## CPC

- A01N 43/54: 1,3-Diazines; Hydrogenated 1,3-diazines
- A01N 37/34: Nitriles
- A01N 37/50: the nitrogen atom being doubly bound to the carbon skeleton
- A01N 43/40: six-membered rings
- A01N 43/56: 1,2-Diazoles; Hydrogenated 1,2-diazoles
- A01N 43/653: 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A01N 43/88: six-membered rings with three ring hetero atoms
- A01N 45/02: having three carbocyclic rings
- A01N 47/04: containing >N—S—C≡(Hal)3 groups
- A01N 47/08: the carbon atom having one or more single bonds to nitrogen atoms
- A01N 47/14: Di-thio analogues thereof
- A01N 47/24: containing the groups [IMAGE cpc-sch-A01N-0944.gif], [IMAGE cpc-sch-A01N-0945.gif] or[IMAGE cpc-sch-A01N-0946.gif]; Thio analogues thereof
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

A fungicidal composition containing a fungicidally effective amount of the compound of Formula I: 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one, and at least one fungicide to provide synergistic control of selected fungi wherein the at least one fungicide is a fungicidal sterol biosynthesis-inhibitor.

## Claims

### Claim 1

A synergistic fungicidal mixture, comprising:
a fungicidally effective amount of the compound of Formula I:
and
at least one additional fungicide in which the at least one additional fungicide is a fungicidal sterol biosynthesis inhibitor.

### Claim 2 (depends on 1)

The mixture of claim 1 in which the at least one additional fungicide is selected from the group consisting of epoxiconazole, cyproconazole, myclobutanil, metconazole, propiconazole, prothioconazole, fluquinconazole, flutriafol, and difenoconazole.

### Claim 3 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to prothioconazole is between about 1:21.6 and about 2:1.

### Claim 4 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to epoxiconazole is between about 3.6:1 and about 20:1.

### Claim 5 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to cyproconazole is between about 1:3 and about 4.5:1.

### Claim 6 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to myclobutanil is between about 1:27 and about 1:4.

### Claim 7 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to metconazole is between about 2.2:1 and about 30:1.

### Claim 8 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to difenoconazole is between about 120:1 and about 787:1.

### Claim 9 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to propiconazole is between about 1:2.1 and about 30:1.

### Claim 10 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to fluquinconazole is between about 1:1.3 and about 170:1.

### Claim 11 (depends on 2)

The mixture of claim 2 in which the concentration ratio of the Compound of Formula I to flutriafol is between about 1:20.6 and about 5.1:1.

### Claim 12 (depends on 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)

The mixtures of claims 1-11, wherein the mixture provides control of a fungal pathogen and the fungal pathogen is one of Leaf Blotch of Wheat (Mycosphaerella graminicola; anamorph: Septoria tritici), Wheat Brown Rust (Puccinia triticina), Stripe Rust (Puccinia striiformis f. sp. tritici), Scab of Apple (Venturia inaequalis), Blister Smut of Maize (Ustilago maydis), Powdery Mildew of Grapevine (Uncinula necator), Barley scald (Rhynchosporium secalis), Blast of Rice (Magnaporthe grisea), Rust of Soybean (Phakopsora pachyrhizi), Glume Blotch of Wheat (Leptosphaeria nodorum), Powdery Mildew of Wheat (Blumeria graminis f. sp. tritici), Powdery Mildew of Barley (Blumeria graminis f. sp. hordei), Powdery Mildew of Cucurbits (Erysiphe cichoracearum), Anthracnose of Cucurbits (Glomerella lagenarium), Leaf Spot of Beet (Cercospora beticola), Early Blight of Tomato (Alternaria solani), and Net Blotch of Barley (Pyrenophora teres).

### Claim 13 (depends on 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)

The mixtures of claims 1-11, wherein the mixture provides control of a fungal pathogen and the fungal pathogen is Leaf Blotch of Wheat (Mycosphaerella graminicola; anamorph: Septoria tritici).

### Claim 14 (depends on 2)

The mixture of claim 2, wherein the mixture provides control of a fungal pathogen and the fungal pathogen is one of Leaf Blotch of Wheat (Mycosphaerella graminicola; anamorph: Septoria tritici), Wheat Brown Rust (Puccinia triticina), Stripe Rust (Puccinia striiformis f. sp. tritici), Scab of Apple (Venturia inaequalis), Blister Smut of Maize (Ustilago maydis), Powdery Mildew of Grapevine (Uncinula necator), Barley scald (Rhynchosporium secalis), Blast of Rice (Magnaporthe grisea), Rust of Soybean (Phakopsora pachyrhizi), Glume Blotch of Wheat (Leptosphaeria nodorum), Powdery Mildew of Wheat (Blumeria graminis f. sp. tritici), Powdery Mildew of Barley (Blumeria graminis f. sp. hordei), Powdery Mildew of Cucurbits (Erysiphe cichoracearum), Anthracnose of Cucurbits (Glomerella lagenarium), Leaf Spot of Beet (Cercospora beticola), Early Blight of Tomato (Alternaria solani), and Net Blotch of Barley (Pyrenophora teres).

### Claim 15 (depends on 2)

The mixture of claim 2, wherein the mixture provides control of a fungal pathogen and the fungal pathogen is Leaf Blotch of Wheat (Mycosphaerella graminicola; anamorph: Septoria tritici).

### Claim 16 (depends on 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11)

A synergistic, fungicidal composition comprising a fungicidally effective amount of the mixtures of claims 1-11 and an agriculturally acceptable adjuvant or carrier.

### Claim 17 (depends on 1)

The mixture of claim 1 in which the at least one additional fungicide is prothioconazole.

### Claim 18 (depends on 1)

The mixture of claim 1 in which the at least one additional fungicide is epoxiconazole.