Bifidobacterium Longum with the Ability to Relieve Atopic Dermatitis and its Application
AssigneeJiangnan University
InventorsJianxin ZHAO, Wenwei LU, Wei CHEN, Zhifeng FANG, Qixiao ZHAI, Bo YANG, Hao ZHANG
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AssigneeJiangnan University
InventorsJianxin ZHAO, Wenwei LU, Wei CHEN, Zhifeng FANG, Qixiao ZHAI, Bo YANG, Hao ZHANG
Estimating the term…
The disclosure discloses Bifidobacterium longum with the ability to relieve atopic dermatitis and its application, and belongs to the technical fields of microorganisms and medicine. The Bifidobacterium longum of the disclosure has the effects of relieving atopic dermatitis, and the effects are specifically embodied in: (1) significantly improving the degree of ear swelling in mice with atopic dermatitis; (2) significantly improving skin pathological symptoms and inflammatory cell infiltration in mice with atopic dermatitis; (3) significantly reducing the serum IgE level in mice with atopic dermatitis; (4) significantly reducing the levels of IL-4 and IL-13 in the skin tissues of mice with atopic dermatitis; and (5) significantly reducing the level of histamine in the skin tissues of mice with atopic dermatitis. Therefore, the Bifidobacterium longum has great application prospects in the preparation of products for the prevention and/or treatment of atopic dermatitis.
A composition comprising Bifidobacterium longum, wherein the Bifidobacterium longum was deposited at the Guangdong Microbial Culture Collection Center on Oct. 11, 2018, with the accession number of GDMCC No. 60461, and the deposit address of 5th Floor, Building No. 59, Courtyard No. 100, Xianlie Middle Road, Guangzhou.
A product for prevention and/or treatment of atopic dermatitis, wherein the product comprises Bifidobacterium longum, the Bifidobacterium longum was deposited at the Guangdong Microbial Culture Collection Center on Oct. 11, 2018, with the accession number of GDMCC No. 60461, and the deposit address of 5th Floor, Building No. 59, Courtyard No. 100, Xianlie Middle Road, Guangzhou, and the product treats or prevents atopic dermatitis.
Dependencies are inferred from the claim text.