Solubilization of poorly soluble cooling substances
AssigneeSymrise AG
InventorsJenny WEISSBRODT, Michael BACKES, Rita LAGES, Olga PAULI
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Abstract
The present invention relates to a cooling composition for producing cooling particles comprising a solvent component and dissolved therein (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-cyclohexane-carboxamide. The present invention further relates to cooling particles comprising a cooling composition according to the invention, oral preparations comprising cooling particles, new uses of cooling particles, a process for the production of cooling particles as well as the use of a solvent component for dissolving cooling agents.
Claims25
A cooling composition for producing cooling particles comprising:
- (A) a solvent component or comprising:
- i) 2-hydroxypropyl (2-isopropyl-5-methyl-cyclohexyl) carbonate, and/or
- ii) (2-isopropyl-5-methyl-cyclohexyl) 2-hydroxypropanoate;
- and
- (B) 0.5 to 12% by weight, based on the total weight of the composition, of (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-cyclohexane-carboxamide (CAS number 68489-09-8;
- FEMA number 4681) as a cooling agent dissolved in the solvent component.
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Dependencies are inferred from the claim text.