Methods, devices, and systems for detecting analyte levels
AssigneeOova, Inc.
InventorsAparna DIVARANIYA, Jerome SCELZA
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Abstract
The present disclosure describes a method of quantifying analyte levels using gold nanoparticles. The present disclosure also describes a device to quantify analyte levels using gold nanoparticles and image processing of pixels isolated from a single vector. The methods, devices, and systems of the disclosure can be used to quantify analytes such as luteinizing hormone, progesterone, estradiol, or testosterone.
Claims43
A computer-implemented method comprising:
- (a) capturing, by a camera of a mobile telecommunications device, an image of a detection region on a substrate in contact with a biological sample from a subject, wherein the detection region comprises a detector that undergoes a change in a visible property of the detection region in response to contact with an analyte in the biological sample, wherein the analyte is associated with a health profile of the subject;
- (b) processing, by a processor of the mobile telecommunications device, pixel intensities of the image of the detection region on the substrate in contact with the biological sample, thereby quantifying an amount of the analyte in the detection region on the substrate to determine a concentration of the analyte in the biological sample, wherein the pixel intensities correspond to the visible property of the detector;
- and
- (c) providing, by the processor of the mobile telecommunications device, a report on the health profile of the subject based on the concentration of the analyte.
A computer program product comprising a non-transitory computer-readable medium having computer-executable code encoded therein, the computer-executable code adapted to be executed to implement a method comprising:
- (a) providing an analyte processing and reporting system of a mobile telecommunications device, wherein the analyte processing and reporting system comprises:
- (i) an optical sensor module;
- (ii) a quantification module;
- and
- (iii) a visualization module;
- (b) capturing, by the optical sensor module, an image of a detection region on a substrate in contact with a biological sample from a subject, wherein the detection region comprises a detector that undergoes a change in a visible property of the detection region in response to contact with an analyte in the biological sample, wherein the analyte is associated with a health profile of the subject;
- (c) processing, by the quantification module, pixel intensities of the image of the detection region on the substrate in contact with the biological sample, thereby quantifying an amount of the analyte in the detection region on the substrate to determine a concentration of the analyte in the biological sample, wherein the pixel intensities correspond to the visible property of the detector;
- and
- (d) providing, by the visualization module, a report on the health profile of the subject based on the concentration of the analyte in the biological sample.
Dependencies are inferred from the claim text.