Radioactive source calibration
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Servic
InventorStephen S. Adler
Life of this patent
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Abstract
Methods and apparatus for calibrating radioactive sources are described. An array of scintillation detectors form a receptacle within which a sample or sample container can be retained by a holder. The scintillation detectors are coupled via light transducers such as photomultiplier tubes (PMTs) to independent electronic counters. Coincidence processing of time-tagged events yields a correlated cent rate. One or more corrections can be applied as needed, for background counts, deadtime, or random coincidences. Voltage tuning of PMTs yields improved reproducibility. Variations are disclosed. 1% accuracy has been demonstrated over a range N of 10 kBq-3 MBq, covering a gap in the capabilities of conventional technology.
Claims21
1-51. (canceled)
An apparatus for calibration of a radioactive sample, the apparatus comprising:
- a receptacle containing a sample chamber and configured to retain the radioactive sample;
- an array of at least three scintillation detectors disposed around the sample chamber;
- an array of light transducers, each light transducer optically coupled to a respective one of the scintillation detectors;
- and
- a plurality of electronic counters comprising an electronic counter for each respective scintillation detector;
- wherein each light transducers is electrically coupled to a respective one of the electronic counters for independently counting radioactive decay events of the radioactive sample detected by the respective scintillation detector.
One or more computer-readable media storing instructions which, when executed by one or more hardware processors, cause the one or more hardware processors to perform operations comprising:
- (a) synchronizing respective counting electronics for an array of at least three particle detectors;
- (b) time-tagging digital packets of particle detection events for each of the particle detectors;
- (c) maintaining respective queues for the particle detectors, wherein time-tagged events of each of the particle detectors are stored in a respective one of the queues;
- (d) maintaining respective pointers to a respective marker event in each of the queues wherein, for any given queue, the time-tagged events earlier than the respective marker event have already been tested for coincidence and the time-tagged events later than the respective marker event have yet to be tested for coincidence;
- (e) selecting an earliest among the marker events;
- (f) determining a number N of other marker events which are in coincidence with the earliest marker event;
- (g) incrementing a counter;
- and
- (h) advancing the pointer to the earliest marker event and, in a case where N≥1, advancing the pointers to the other marker events which are in coincidence with the earliest marker event.
A method for calibrating a radioactive sample, comprising:
- providing a plurality of scintillation detectors coupled by photodetectors to respective counting electronics;
- tuning bias power supply outputs coupled to the photodetectors so that photopeaks of particles emitted by a radioactive calibration source appear at aligned energy channels at the respective counting electronics;
- positioning a sample container containing the radioactive sample at a central location amid the scintillation detectors;
- time-tagging decay events detected at the scintillation detectors, independently for each scintillation detector;
- detecting coincidences among the time-tagged decay events from two or more of the scintillation detectors;
- aggregating time-tagged decay events from the scintillation detectors, with coincidences being singly counted, to obtain a correlated event rate;
- determining a radioactivity level of the radioactive sample from the correlated event rate;
- and
- reporting the determined radioactivity level.
Dependencies are inferred from the claim text.