Detection of bacteria using bacteriophage
AssigneesUniversity of Pittsburgh—Of the Commonwealth System of Higher Education, Duquesne University of the Holy Spirit
InventorsJOHN ALSTON KELLUM, JOHN D. HEMPEL, ROBERT HUGH EDGAR, JOHN ANDREW VIATOR
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Abstract
A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
Claims20
A method of determining if a sample taken from a patient includes a species, strain or type of bacteria, comprising:
- mixing a labeled bacteriophage including a label that is detectible via a detection system with the sample, the labeled bacteriophage being active to selectively bind with the species, strain or type of bacteria and using the detection system to determine the presence of the labeled bacteriophage bound to the species, strain or type of bacteria.
A bacteriophage comprising a label attached thereto, wherein the label is selected to be detectible via a detection system.
A system for determining if a sample includes at least one species, strain or type of bacteria, comprising:
- a plurality of bacteriophages, each of the plurality of bacteriophages selectively binding with a different species, strain or type of bacteria, each of the plurality of bacteriophages including a different label that is separately detectable via a detection system.
A system for identifying at least one species, strain or type of bacteria in a sample, comprising:
- at least one a labeled bacteriophage which binds selectively to the species, strain or type of bacteria, the at least one labeled bacteriophage comprising a label attached thereto, the system further comprising a detection system adapted to detect the labeled bacteriophage bound to the species of bacteria.
Dependencies are inferred from the claim text.