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US 2021/0261670 A1Published application
Novel anti-bmpr1b antibodies and methods of use
AssigneeAbbvie Stemcentrx LLC
InventorsSOMDUTTA ROY, LAURA SAUNDERS, CASEY FRANKLIN, KEVIN MARTINEZ, SARAH FONG, ZHAO HUANG, SILVIA JUAREZ, ALINA HE, KATHRYN A. LOVING, SANDRO VIVONA
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Abstract
Provided are novel anti-BMPR1B antibodies and antibody drug conjugates, and methods of using such anti-BMPR1B antibodies and antibody drug conjugates to treat cancer.
Claims21
1-58. (canceled)
An isolated antibody that binds to BMPR1B and comprises three complementarity determining regions of a light chain variable region set forth as SEQ ID NO:
- 21 and three complementarity determining regions of a heavy chain variable region set forth as SEQ ID NO:
- 23.
A pharmaceutical composition comprising an antibody conjugated to a payload, wherein the antibody comprises a light chain variable region set forth as SEQ ID NO:
- 21 and a heavy chain variable region set forth as SEQ ID NO:
- 23.
Dependencies are inferred from the claim text.